Volume No. :   2

Issue No. :  2

Year :  2012

ISSN Print :  2231-5705

ISSN Online :  2231-5713


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Analgesic Activity of Methanol Extract of Plumbago indica (L.) by Acetic Acid Induced Writhing Method



Address:   Swati Paul *, Dibyajyoti Saha
Department of Pharmacy, BGC Trust University, Bangladesh, Chittagong
*Corresponding Author
DOI No:

ABSTRACT:
The present study was designed to investigate Analgesic activity of methanolic extract of Plumbago indica (L.) using Acetic Acid Induced Writhing method. Methanolic extract was administered intraperitoneally at doses of 250 mg/kg and 500 mg/kg to Young Swiss-albino mice. Methanol Extract of Plumbago indica (L.) showed significant inhibition in pain response induced by thermal and mechanical stimuli in dose dependent manner. The obtained results provide promising baseline information for the potential use of these crude extract in the treatment of pain.
KEYWORDS:
Plumbago indica (L.), analgesic, Acetic Acid, Writhing Method.
Cite:
Swati Paul , Dibyajyoti Saha. Analgesic Activity of Methanol Extract of Plumbago indica (L.) by Acetic Acid Induced Writhing Method. Asian J. Pharm. Tech. 2(2): April-June 2012; Page 74-76.
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