Volume No. :   4

Issue No. :  4

Year :  2014

ISSN Print :  2231-5705

ISSN Online :  2231-5713


Registration

Allready Registrered
Click to Login

Synthesis and Evaluation of Some New Imidazole Derivatives for their Anti-Microbial and Anti-Inflammatory activities



Address:   Hemlata Bhawar1*, Nachiket Dighe1, Pankaj Shinde1, Ravi Lawre2 and Sanjay Bhawar3
1Department of Pharmaceutical Chemistry, Pravara Rural College of Pharmacy, Loni, MS, India-413736.
2Department of Quality Assurance Technique, Pravara Rural College of Pharmacy, Loni, MS, India-413736.
3Department of Pharmacology, Pravara Rural College of Pharmacy, Loni, MS, India-413736.
*Corresponding Author
DOI No:

ABSTRACT:
The synthesis, structure and biological activity of Imidazole derivatives have long been the focus of research interests in the field of Medicinal Chemistry. A number of Imidazole derivatives have been reported to possess interesting biological activities such as Antimicrobial, Anti-inflammatory and Antifungal activities etc. Around 22 new derivatives were synthesized, with the standard chemicals and well established procedures. The synthesized compounds were tested for their preliminary tests, physical constants, TLC etc. IR, 1H-NMR Spectra and CHN analysis confirmed the structures of the final compounds. The proposed compounds were screened for their antimicrobial and anti-inflammatory activities with the standard drugs in the well-equipped microbiology and pharmacology lab by using standard methods.
KEYWORDS:
Anti-inflammatory, Antimicrobial and Imidazole
Cite:
Hemlata Bhawar, Nachiket Dighe, Pankaj Shinde, Ravi Lawre, Sanjay Bhawar. Synthesis and Evaluation of Some New Imidazole Derivatives for their Anti-Microbial and Anti-Inflammatory activities. Asian J. Pharm. Tech. 2014; Vol. 4: Issue 4, Oct.-Dec., Pg 189-194.
[View HTML]      [View PDF]



Visitor's No. :   105239