Volume No. :   5

Issue No. :  1

Year :  2015

ISSN Print :  2231-5705

ISSN Online :  2231-5713


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A Review- Emerging Use of Nano-Based Carriers in Diagnosis and Treatment of Cancer-Novel Approaches



Address:   Mohd. Yaqub Khan1*, Brijesh Kumar Saroj2, Maryada Roy3, Dr. Irfan Aziz4
1Azad Institute of Pharmacy & Research Azadpur, Adjacent CRPF Camp, Bijnour, Lucknow - 226 002, Uttar Pradesh, India
2Goel Institute of Pharmacy & Sciences, Lucknow, Uttar Pradesh, India
3Mangalayatan University, Beswan, Aligarh, Uttar Pradesh, India
4Azad Institute of Pharmacy & Research Azadpur, Adjacent CRPF Camp, Bijnour, Lucknow - 226 002, Uttar Pradesh, India
*Corresponding Author
DOI No: 10.5958/2231-5713.2015.00008.2

ABSTRACT:
Despite intensive research efforts, cancer remains one of the leading causes of death in the world. Many new methods and techniques have been developed in order to improve diagnosis and treatment, often promising in the beginning, but with limited results during the course of their application. In recent years, there has been an unprecedented expansion in the field of nanomedicine with the development of new nanoparticles for the diagnosis and treatment of cancer. Nanoparticles have unique biological properties given their small size and large surface area-to-volume ratio, which allows them to bind, absorb, and carry compounds such as small molecule drugs, DNA, RNA, proteins, and probes with high efficiency. Their tunable size, shape, and surface characteristics also enable them to have high stability, high carrier capacity, the ability to incorporate both hydrophilic and hydrophobic substances and compatibility with different administration routes, thereby making them highly attractive in many aspects of oncology. The expansion of novel nanoparticles for drug delivery is an exciting and challenging research filed, in particular for the delivery of emerging cancer therapies, including small interference RNA (siRNA) and microRNA (miRNAs)-based molecules.
KEYWORDS:
Nonomedicine, Nanoparticles, Oncology.
Cite:
Mohd. Yaqub Khan, Brijesh Kumar Saroj, Maryada Roy, Irfan Aziz. A Review- Emerging Use of Nano-Based Carriers in Diagnosis and Treatment of Cancer-Novel Approaches. Asian J. Pharm. Tech. 2015; Vol. 5: Issue 1, Pg 38-49.
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