Volume No. :   5

Issue No. :  3

Year :  2015

ISSN Print :  2231-5705

ISSN Online :  2231-5713


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An Overview about Medicinal Chemistry and Pharmaceutical Applications of 2, 4-Imidazolidinone and its Derivatives



Address:   Bhadreshkumar R. Sudani1* and Vikas A. Desai2
1Government Engineering College, Valsad, Near Sanskar Kendra, Tithal Road, Valsad-396001
2 B.K.M. Science College, Near Sanskar Kendra, Tithal Road, Valsad-396001
*Corresponding Author
DOI No: 10.5958/2231-5713.2015.00022.7

ABSTRACT:
2,4-imidazolidinedione is a heterocyclic compound commonly well known as Hydantoin. Starting from its first synthesis it is found interesting among the medicinal and pharmaceutical chemists. In this review article we have briefly described different methods of synthesis with the help of some name reactions like Buchere-Bergs reaction and Diels-Alder reaction. It is found that this molecule is synthesized with three substitutions where different organic reactive groups imports different pharmacological properties in the molecules of hydantoin derivatives. The broad pharmacological activities of 2,4-imidazolidinedione is also discussed in this work for more than 16 dieses. This review article will be very good useful for scholars and scientists to explore more possibilities with other derivatives using the methods given in this review paper.
KEYWORDS:
Hydantoin, Allantoin , Imidazolidinedione, Heterocyclic, phenyl urea.
Cite:
Bhadreshkumar R. Sudani, Vikas A. Desai. An Overview about Medicinal Chemistry and Pharmaceutical Applications of 2, 4-Imidazolidinone and its Derivatives. Asian J. Pharm. Tech. 2015; Vol. 5( 3) 153-157.
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