Volume No. :   7

Issue No. :  2

Year :  2017

ISSN Print :  2231-5705

ISSN Online :  2231-5713


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Utility of Autoclave in the Synthesis of Organic Compounds



Address:   Ulhas Balkrishna Hadkar1*, Poonam Rajesh Advani2, Radhika Kishore Raheja2
1Director and Professor, Mumbai Educational Trust Institute of Pharmacy, Bandra (West), Mumbai-400050
2Associate Professor, Mumbai Educational Trust Institute of Pharmacy, Bandra (West), Mumbai-400050
*Corresponding Author
DOI No: 10.5958/2231-5713.2017.00017.4

ABSTRACT:
Synthesis of Benzimidazole and 2-Methylbenzimidazole from o-Phenylenediamine has been reported by conventional method of heating the reaction mixture on a water bath. Synthesis of Benzoic acid from Benzaldehyde by Cannizzaro reaction has also been reported. The authors of this article have synthesized these compounds by heating the reaction mixture in an autoclave. The yield obtained was found to be greater than that obtained using reported conventional methods, which emphasizes the utility of autoclave in the synthesis of organic compounds. The structure of synthesized compound was confirmed by Fourier-Transform Infrared Spectroscopy (FT-IR)
KEYWORDS:
Synthesis, autoclave, Benzimidazole, 2-Methylbenzimidazole, Benzoic acid, Cannizzaro reaction.
Cite:
Ulhas Balkrishna Hadkar, Poonam Rajesh Advani, Radhika Kishore Raheja. Utility of Autoclave in the Synthesis of Organic Compounds. Asian J. Pharm. Tech. 2017; 7(2): 103-104.
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