Volume No. :   7

Issue No. :  4

Year :  2017

ISSN Print :  2231-5705

ISSN Online :  2231-5713


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Formulation and Evaluation of Controlled Release tablets of Aspirin



Address:   Chinmaya Keshari Sahoo1, K. Satyanarayana2, D. Venkata Ramana3, Kanhu Charan Panda4
1Assistant Professor, Department of Pharmaceutics, Malla Reddy College of Pharmacy, Maisammaguda, Secunderabad, Telangana-500014.
2Professor and Principal, Department of Pharmacognosy, Princeton College of Pharmacy, Korremula, Ghatkesar, R. R. District, Telangana-500088
3Professor, Department of Pharmaceutical Technology, Netaji Institute of Pharmaceutical Sciences, Toopranpet, Yadadri Bhongir, Telangana-508252
4Associate Professor, Department of Pharmaceutics, Anwarul Uloom College of Pharmacy, Newmallepally, Hyderabad, Telangana
*Corresponding Author
DOI No: 10.5958/2231-5713.2017.00034.4

ABSTRACT:
The present work was aimed to develop controlled release tablets of aspirin. Direct compression technique was adopted for the preparation of all these formulations. The developed tablets were evaluated for pre compression parameters; post compression parameters, in vitro dissolution study. Among all the developed batches ASF3 showed highest drug release 96.14% at the end of 10 h. The optimized formulation was found to be stable up to 3 months when tested for stability study at 40±2ºC/ 75±5% RH.
KEYWORDS:
Aspirin, direct compression, in vitro drug release, stability study
Cite:
Chinmaya Keshari Sahoo, K. Satyanarayana, D. Venkata Ramana, Kanhu Charan Panda. Formulation and Evaluation of Controlled Release tablets of Aspirin. Asian J. Pharm. Tech. 2017; 7 (4): 229-233.
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