Volume No. :   8

Issue No. :  2

Year :  2018

ISSN Print :  2231-5705

ISSN Online :  2231-5713


Registration

Allready Registrered
Click to Login

Evaluation Ixora coccinea Formulation for antibacterial and antioxidant activity.



Address:   Prof. Sushil D. Patil*, Bhavini D. Chande, Kirti M. Budukhale, Radhika V. Damare, Nilam Kale, Shivangi S. Pathak
Department of Pharmaceutical Chemistry, MET's Institute of Pharmacy, Bhujbal Knowledge City, Adgaon Nashik, Maharashtra, India.
*Corresponding Author
DOI No: 10.5958/2231-5713.2018.00014.4

ABSTRACT:
Present investigation was to develop novel formulation methanolic extract of Ixora coccinea leaves (ICF-ME), which is reported to possess Anti-oxidant activityanti-bacterial activitiesandantimicrobial activity. Ixora coccinea formulation showed significant activities antibacterial andantioxidant assays compared to the standardantioxidant in a dose dependent manner andremarkable activities to scavenge reactive oxygen species (ROS). Staphylococcus aureus and E. coli was evaluated by the standard cup plate method and the inhibition zone diameters were measured for antibacterial activity. It is evident that formulation F-4 containing both clove oil (0.7%) and Ixora coccinea (7%) showed larger zone of inhibition in comparison to other formulations.So antibacterial and antioxidant activity of formulation F-4 found to be superior to other formulations. Results of all other evaluation parameters of F-4 were also satisfactory among all the formulations.
KEYWORDS:
formulation, antioxidantactivity, Ixora coccinea, antibacterial.
Cite:
Sushil D. Patil, Bhavini D. Chande, Kirti M. Budukhale, Radhika V. Damare, Nilam Kale, Shivangi S. Pathak. Evaluation Ixora coccinea Formulation for antibacterial and antioxidant activity. Asian J. Pharm. Tech. 2018; 8 (2):88-91.
[View HTML]     



Visitor's No. :   90725