Volume No. :   8

Issue No. :  3

Year :  2018

ISSN Print :  2231-5705

ISSN Online :  2231-5713


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Controlled Drug Delivery System-A Novel Approach



Address:   Pradnya M. Khandagale1*, Manish M. Rokade2, Prof. Dipti G. Phadtare3
1Department of Quality Assurance Technique, R.G.Sapkal Institute of Pharmacy, Anjaneri, Nashik.
2Department of pharmaceutics, R.G Sapkal Institute of Pharmacy, Anjaneri, Nashik.
3Department of Pharmaceutical Chemistry, R.G. Sapkal Institute of Pharmacy, Anjaneri, Nashik.
*Corresponding Author
DOI No: 10.5958/2231-5713.2018.00026.0

ABSTRACT:
The drug delivery scientists need to reexamine the advances made during the past 60 years, analyze our current abilities, and design the future technologies that will propel us to achieve the next level of drug delivery technologies. History shows that the first generation (1G) of drug delivery research during 1950–1980 was quite productive, while the second generation (2G) technologies developed during 1980–2010 were not as prolific. The ultimate goal of drug delivery research is to develop clinically useful formulations to treat various diseases. Effective drug delivery systems can be developed by overcoming formulation barriers and/or biological barriers. Controlled release drug delivery systems provide uniform concentration of drug to the absorption site and thus allow the maintenance of plasma concentration within the therapeutic range which minimizes not only the side effects but also the frequency of administration. Oral Sustained release (SR) products provide an advantage over conventional dosage forms by optimizing properties of drugs in such a way that it reduces dosing frequency to an extent that once daily dose is sufficient for therapeutic management through uniform plasma concentration providing maximum utility of drug with reduction in local and systemic side effects and cure or control condition in shortest possible time by smallest quantity of drug to assure greater patient compliance.
KEYWORDS:
Drug delivery, History, Controlled drug delivery system, Sustained drug delivery system, Pre-determined rate.
Cite:
Pradnya M. Khandagale, Manish M. Rokade, Prof. Dipti G. Phadtare. Controlled Drug Delivery System-A Novel Approach. Asian J. Pharm. Tech. 2018; 8 (3):161-164.
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