Author(s): Arjun Singh


DOI: 10.52711/2231-5713.2022.00055   

Address: Arjun Singh*
Department of Medicine, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA 19107, United States.
*Corresponding Author

Published In:   Volume - 12,      Issue - 4,     Year - 2022

Traditional medicine is a body of knowledge, skills, and practices based on traditional cultures' presumptions, beliefs, and experiences in order to maintain their health. Traditional herbal treatments are highly valued among many rural or indigenous people in many underdeveloped nations. According to the World Health Organization, about 80% of the world's population relies on traditional medicine, with 60% of rural Indians using herbal treatments. During the previous five years, utilization of herbal supplements grew from 2.5% to 12 percent. The assessment of novel medications, particularly phytochemically derived materials, has opened up a large arena for study and has aided India's shift from traditional to modern medicine. Tannins, alkaloids, carbohydrates, terpenoids, steroids, flavonoids, and phenols are some of the chemical components found in medicinal plants that have a distinct physiological effect on the human body. Medicinal plants do not only exhibit natural therapeutic properties, but also provide natural prevention against various diseases. As a result, we are attempting to summarize, gather the number of plants, and their ethnopharmacological qualities in this complete review study research.

Cite this article:
Arjun Singh. A Review of various aspects of the Ethnopharmacological, Phytochemical, Pharmacognostical, and Clinical significance of selected Medicinal plants. Asian Journal of Pharmacy and Technology; 12(4):349-0. doi: 10.52711/2231-5713.2022.00055

Arjun Singh. A Review of various aspects of the Ethnopharmacological, Phytochemical, Pharmacognostical, and Clinical significance of selected Medicinal plants. Asian Journal of Pharmacy and Technology; 12(4):349-0. doi: 10.52711/2231-5713.2022.00055   Available on:

1.    World Health Organization. WHO traditional medicine strategy: 2014-2023. World Health Organization, 2013.
2.    World Health Organization. WHO global report on traditional and complementary medicine 2019. World Health Organization, 2019.
3.    Qi, Zhang. "Who traditional medicine strategy. 2014-2023." Geneva: World Health Organization 188 (2013).
4.    World Health Organization. "The regional strategy for traditional medicine in the Western Pacific (2011-2020)." (2012).
5.    World Health Organization. Regional strategy for traditional medicine in the Western Pacific. Manila: WHO Regional Office for the Western Pacific, 2002.
6.    Kasilo, Ossy MJ, and Jean‐Baptiste Nikiema. "World Health Organization perspective for traditional medicine." Novel Plant Bioresources: Applications in Food, Medicine and Cosmetics (2014): 23-42.
7.    Zhang, Qi, Aditi Sharan, Stéphane Alexandre Espinosa, Daniel Gallego-Perez, and John Weeks. "The path toward integration of traditional and complementary medicine into health systems globally: The World Health Organization report on the implementation of the 2014–2023 strategy." The Journal of Alternative and Complementary Medicine 25, no. 9 (2019): 869-871.
8.    P. Jaya Preethi. Herbal Medicine for Diabetes Mellitus: A Review. Asian J. Pharm. Res. 3(2): April- June 2013; Page 57-70. Lakshmi, K. “Effectiveness of Nursing Care of Antenatal Mothers with Gestational Diabetes Mellitus.” Asian Journal of Nursing Education and Research 10, no. 3 (2020): 286.
9.    Raju, Vidya, Jasmine Joy Bell, N. J. Merlin, and Shaiju S Dharan. “Ethno Pharmacological Uses of Artocarpus Altilis -A Review.” Asian Journal of Pharmaceutical Research 7, no. 4 (2017): 239.
10.    Somwanshi, Sachin B., Punam D. Bairagi, and Kiran B. Kotade. “Study of Gestational Diabetes Mellitus: A Brief Review.” Asian Journal of Pharmaceutical Research 7, no. 2 (2017): 118.
11.    Yousaf, Aqsa, and Sammia Shahid. “The Study of Anethum Graveolens L. (Dill) in the Case of Diabetes Mellitus (DM).” Asian Journal of Research in Pharmaceutical Science 10, no. 4 (2020): 248–56.
12.    Chanda, D., Prieto-Lloret, J., Singh, A., Iqbal, H., Yadav, P., Snetkov, V., Aaronson, P.I., 2016. Glabridin-induced vasorelaxation: Evidence for a role of BKCa channels and cyclic GMP. Life Sciences 165, 26–34.
13.    Gautam, Y., Dwivedi, S., Srivastava, A., Hamidullah, Singh, A., Chanda, D., Singh, J., Rai, S., Konwar, R., Negi, A.S., 2016. 2-(3′,4′-Dimethoxybenzylidene) tetralone induces anti-breast cancer activity through microtubule stabilization and activation of reactive oxygen species. RSC Adv. 6, 33369–33379.
14.    Hamid, A.A., Hasanain, M., Singh, A., Bhukya, B., Omprakash, Vasudev, P.G., Sarkar, J., Chanda, D., Khan, F., Aiyelaagbe, O.O., Negi, A.S., 2014. Synthesis of novel anticancer agents through opening of spiroacetal ring of diosgenin. Steroids 87, 108–118.
15.    Hamid, A.A., Kaushal, T., Ashraf, R., Singh, A., Chand Gupta, A., Prakash, O., Sarkar, J., Chanda, D., Bawankule, D.U., Khan, F., Shanker, K., Aiyelaagbe, O.O., Negi, A.S., 2017. (22β,25R)-3β-Hydroxy-spirost-5-en-7-iminoxy-heptanoic acid exhibits anti-prostate cancer activity through caspase pathway. Steroids 119, 43–52.
16.    Jain, S., Singh, A., Khare, P., Chanda, D., Mishra, D., Shanker, K., Karak, T., 2017. Toxicity assessment of Bacopa monnieri L. grown in biochar amended extremely acidic coal mine spoils. Ecological Engineering 108, 211–219.
17.    Khwaja, S., Fatima, K., Hasanain, M., Behera, C., Kour, A., Singh, A., Luqman, S., Sarkar, J., Chanda, D., Shanker, K., Gupta, A.K., Mondhe, D.M., Negi, A.S., 2018. Antiproliferative efficacy of curcumin mimics through microtubule destabilization. European Journal of Medicinal Chemistry 151, 51–61.
18.    Kumar, B.S., Ravi, K., Verma, A.K., Fatima, K., Hasanain, M., Singh, A., Sarkar, J., Luqman, S., Chanda, D., Negi, A.S., 2017. Synthesis of pharmacologically important naphthoquinones and anticancer activity of 2-benzyllawsone through DNA topoisomerase-II inhibition. Bioorganic and Medicinal Chemistry 25, 1364–1373.
19.    Mishra, D., Jyotshna, Singh, A., Chanda, D., Shanker, K., Khare, P., 2019. Potential of di-aldehyde cellulose for sustained release of oxytetracycline: A pharmacokinetic study. International Journal of Biological Macromolecules 136, 97–105.
20.    Sathish Kumar, B., Kumar, A., Singh, J., Hasanain, M., Singh, A., Fatima, K., Yadav, D.K., Shukla, V., Luqman, S., Khan, F., Chanda, D., Sarkar, J., Konwar, R., Dwivedi, A., Negi, A.S., 2014a. Synthesis of 2-alkoxy and 2-benzyloxy analogues of estradiol as anti-breast cancer agents through microtubule stabilization. European Journal of Medicinal Chemistry 86, 740–751.
21.    Sathish Kumar, B., Singh, Aastha, Kumar, A., Singh, J., Hasanain, M., Singh, Arjun, Masood, N., Yadav, D.K., Konwar, R., Mitra, K., Sarkar, J., Luqman, S., Pal, A., Khan, F., Chanda, D., Negi, A.S., 2014b. Synthesis of neolignans as microtubule stabilisers. Bioorganic and Medicinal Chemistry 22, 1342–1354.
22.    Singh, A., Kumar, B.S., Alam, S., Iqbal, H., Shafiq, M., Khan, F., Negi, A.S., Hanif, K., Chanda, D., 2017. Diethyl-4,4ʹ-dihydroxy-8,3ʹ-neolign-7,7ʹ-dien-9,9ʹ-dionate exhibits AH activity in rats through increase in intracellular cGMP level and blockade of calcium channels. European Journal of Pharmacology 799, 84–93.
23.    Singh, A., Kumar, B.S., Iqbal, H., Alam, S., Yadav, P., Verma, A.K., Khan, F., Shanker, K., Hanif, K., Negi, A.S., Chanda, D., 2019. AH activity of diethyl-4,4’-dihydroxy-8,3’-neolign-7,7’-dien-9,9’-dionate: A continuation study in L-NAME treated wistar rats. Eur. J. Pharmacol. 858, 172482.
24.    Singh, A., Mohanty, I., Singh, J., Rattan, S., 2020. BDNF augments rat internal anal sphincter smooth muscle tone via RhoA/ROCK signaling and nonadrenergic noncholinergic relaxation via increased NO release. American Journal of Physiology-Gastrointestinal and Liver Physiology 318, G23–G33.
25.    Singh, A., Rattan, S., 2021. BDNF rescues aging-associated internal anal sphincter dysfunction. American Journal of Physiology-Gastrointestinal and Liver Physiology 321, G87–G97.
26.    Singh, A., Singh, J., Rattan, S., 2021. Evidence for the presence and release of BDNF in the neuronal and non‐neuronal structures of the internal anal sphincter. Neurogastroenterology and Motility.
27.    Singh, Aastha, Fatima, K., Singh, Arjun, Behl, A., Mintoo, M.J., Hasanain, M., Ashraf, R., Luqman, S., Shanker, K., Mondhe, D.M., Sarkar, J., Chanda, D., Negi, A.S., 2015. Anticancer activity and toxicity profiles of 2-benzylidene indanone lead molecule. European Journal of Pharmaceutical Sciences 76, 57–67.
28.    Singh, Aastha, Fatima, K., Srivastava, A., Khwaja, S., Priya, D., Singh, Arjun, Mahajan, G., Alam, S., Saxena, A.K., Mondhe, D.M., Luqman, S., Chanda, D., Khan, F., Negi, A.S., 2016. Anticancer activity of gallic acid template-based benzylidene indanone derivative as microtubule destabilizer. Chem Biol Drug Des 88, 625–634.
29.    Yadav, P., Iqbal, H., Kumar, K., Kumar, P., Mishra, D., Singh, A., Pal, A., Mukhopadhyay, P., Vamadevan, B., Singh, D., Negi, A.S., Chanda, D., 2022. 2-Benzyllawsone protects against polymicrobial sepsis and vascular hyporeactivity in swiss albino mice. European Journal of Pharmacology 917, 174757.
30.    Manmohan, S., Arjun, S., Khan, S. P., Eram, S., and Sachan, N. K., 2012. Green chemistry potential for past, present and future perspectives. International Research Journal of Pharmacy, 3, 31-36.
31.    Singh A, Kumar BS, Alam S, Iqbal H, Shafiq M, Khan F, Negi AS, Hanif K, Chanda D. Corrigendum to "Diethyl-4,4'-dihydroxy-8,3'-neolign-7,7'-dien-9,9'-dionate exhibits AH activity in rats through increase in intracellular cGMP level and blockade of calcium channels" [Eur. J. Pharmacol. 799 (2017) 84-93]. Eur J Pharmacol. 2017 Jul 5;806:111. doi: 10.1016/j.ejphar.2017.04.033. Erratum for: Eur J Pharmacol. 2017 Mar 15;799:84-93. PMID: 28495016.
32.    Singh, A., R. Sharma, K. M. Anand, S. P. Khan, and N. K. Sachan. "Food-drug interaction." International Journal of Pharmaceutical and Chemical Science 1, no. 1 (2012): 264-279.
33.    Thanh-Hoang, N.-V.; Loc, N.; Nguyet, D.; Thien-Ngan, N.; Khang, T.; Cao, H.; Le, L. Plant Metabolite Databases: From Herbal Medicines to Modern Drug Discovery. J. Chem. Inf. Model. 2020, 60, 1101–1110.
34.    Kumar, S.; Malhotra, R.; Kumar, D. Euphorbia hirta: Its chemistry, traditional and medicinal uses, and pharmacological activities. Pharmacogn. Rev. 2010, 4, 58–61.
35.    Ramu, F.A.; Kumar, S.R. Scientific evaluation of traditionally known insulin plant Costus species for the treatment of diabetes in human. Int. J. Curr. Res. Biosci. Plant Biol. 2016, 3, 87–91.
36.    Jayasri, M. A.; Gunasekaran, S.; Radha, A.; Mathew, T. L. Antidiabetic effect of Costus pictus leaves in normal and streptozotocin-induced diabetes rats. Int. J. Diabetes Metab. 2008, 16, 117–122.
37.    Sidhu, A.K.; Wani, S.; Tamboli, P.S.; Patil, S.N. In Vitro Evaluation of Anti-Diabetic Activity of Leaf and Callus Extracts of Costus pictus. Int. J. Recent Sci. Res. 2014, 3, 1622–1625.
38.    Prakash, K.; Harini, H.; Rao, A.; Rao, P. N. A reviewonIsulin plant (CostusigneusNak). Pharmacogn. Rev. 2014, 8, 67–72.
39.    Radha Devi, G. M. A Comprehensive Review On Costus Pictus D. Don. Int .J. Pharm. Sci. Res. 2019, 10, 3187–3195.
40.    Dhar, M.L., Dhar, M.M., Dhawan, B.N., Mehrotra, B.N., Ray, C. 1968. Screening of Indian plants for biological activity. Indian Journal of Experimental Biology 6 (4), 232-247.
41.    Dhawan, B.N., Dubey, M.P., Mehrotra, B.N., Rastogi, R.P., Tandon, J.S. 1980. Screening of Indian plants for biological activity. Part 9. Indian Journal of Experimental Biology 18, 594-606.
42.    Chattopadhyay, R.R. 1999. A comparative evaluation of some blood sugar lowering agents of plant origin. Journal of Ethnopharmacol- ogy 67 (3), 367-372.
43.    Joglekar, G.V., Chaudhary, N.Y., Aiaman, R. 1959. Effect of Indian medicinal plants on glucose absorption in mice. Indian Journal of Physiology and Pharmacology 3, 76-77.
44.    Panlasigui, L.N., Panlilio, L.M., Madrid, J.C. 1995. Glycemic response in normal subjects to five different legumes commonly used in the Philippines. International Journal of Food Science and Nutrition 46 (2), 155-160.
45.    Marles, R.J., Farnsworth, N.R. 1995. Antidiabetic plants and their active constituents. Phytomedicine 2, 133-189.
46.    Rao, P.V., Ushabala, P., Seshiah, V., Ahuja, M.M., Mather, H.M. 1989. The Eluru survey: prevalence of known diabetes in a rural Indian population. Diabetes Research and Clinical Practice 7 (1), 29-31.
47.    Bading Taika, B., Bouckandou, M., Souza, A., BourobouBourobou, H.P., MacKenzie, L.S., Lione, L., 2018. An overview of anti-diabetic plants used in Gabon: Pharmacology and toxicology. Journal of Ethnopharmacology 216, 203–228.
48.    Chin, Y., Balunas, M., Chai, H., Kinghorn, A., 2006. Drug Discovery From Natural Sources. The AAPS Journal 08, E239–E239.
49.    Choudhury, H., Pandey, M., Hua, C.K., Mun, C.S., Jing, J.K., Kong, L., Ern, L.Y., Ashraf, N.A., Kit, S.W., Yee, T.S., Pichika, M.R., Gorain, B., Kesharwani, P., 2018. An update on natural compounds in the remedy of diabetes mellitus: A systematic review. Journal of Traditional and Complementary Medicine 8, 361–376
50.    Cornwell, T., Cohick, W., Raskin, I., 2004. Dietary phytoestrogens and health. Phytochemistry 65, 995–1016.
51.    Newman, D.J., Cragg, G.M., 2016. Natural Products as Sources of New Drugs from 1981 to 2014. J. Nat. Prod. 79, 629–661.
52.    Newman, D.J., Cragg, G.M., 2012. Natural products as sources of new drugs over the 30 years from 1981 to 2010. J. Nat. Prod. 75, 311–335.
53.    Rao, M.U., Sreenivasulu, M., Chengaiah, B., Reddy, K.J., Chetty, C.M., n.d. Herbal Medicines for Diabetes Mellitus: A Review 11.
54.    Ward, R.S., 1999. Lignans, neolignans and related compounds. Nat. Prod. Rep. 16, 75–96.
55.    Mohd. Yaqub Khan, Irfan Aziz, Bipin Bihari, Hemant Kumar, Maryada Roy, Vikas Kumar Verma. A Review- Phytomedicines Used in Treatment of Diabetes. Asian J. Pharm. Res. 4(3): July-Sept. 2014; Page 135-154.
56.    Vidya Raju, Jasmine Joy Bell, Merlin. N. J, Shaiju S Dharan. Ethno Pharmacological Uses of Artocarpus altilis– A Review. Asian J. Pharm. Res. 2017; 7(4): 239-243. doi: 10.5958/2231-5691.2017.00037.5
57.    Rahul Vikram Singh, Prabhakar Semwal, Taranjeet Kapoor. Medicinal Potential of Six Different Plant Species of Dehradun District, Uttarakhand. Asian J. Res. Pharm. Sci. 4(3): July-Sept. 2014; Page 134-139.
58.    Vaibhav S. Suryawanshi, Akshay R. Yadav, Rushikesh M. Birajdar, Nisha M. Jagtap, Ganesh B. Vambhurkar, Pramod A. Patil. Optimization of Ayurvedic Herbal Medicines by Nanoformulation. Asian J. Res. Pharm. Sci. 2019; 9(1):55-56. doi: 10.5958/2231-5659.2019.00009.2
59.    Sushmita V. Patil, Vaishnavi K. Patil, Paresh A. Patil. Review on Herbal medicines of Alzheimer’s Disease. Asian J. Res. Pharm. Sci. 2020; 10(3):171-177. doi: 10.5958/2231-5659.2020.00033.8
60.    Rchana R. Pawar, Dattaprasad N. Vikhe, R. S. Jadhav. Recent Advances in Extraction Techniques of Herbals – A Review. Asian J. Res. Pharm. Sci. 2020; 10(4):287-292. doi: 10.5958/2231-5659.2020.00050.8

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