Author(s):
Habeeba S. Shaikh, Siddiqua S. Shaikh
Email(s):
habibashaikh762@gmail.com
DOI:
10.52711/2231-5713.2021.00039
Address:
Habeeba S. Shaikh1*, Siddiqua S. Shaikh2
1Department of Pharmacognosy, Pravara Rural College of Pharmacy, Pravaranagar, Maharashtra, India.
2Department of Pharmaceutical Chemistry, SND College of Pharmacy, Babhulgaon Yeola, Maharashtra, India.
*Corresponding Author
Published In:
Volume - 11,
Issue - 3,
Year - 2021
ABSTRACT:
Psoralea corylifolia (Leguminosae) commonly known as babchi or babachi has been used in different traditional system of various aliments since, ancient time. Psoralea corylifolia grow throughout Asia and India or many other countries. This article aims to provide a comprehensive review on the phytochemical and pharmacological aspect of Psoralea corylifolia. In traditional medicine, it has been used in treatment of various diseases such as leucoderma skin diseases, cardiovascular diseases, nephritis, osteoporosis, and cancer vitiligo, poisoning, for conception, caries, deafness, filarial. The stem, seeds, leaves, of this plant containe a variety of biologically active compound such as flavonoids, coumarins, phenols, benzofurans, benzopyrans, quinines, sesquiterpenoids, triterpenoids, steroids, and some other components. Those have varuous medicinal properties. The different part of the plant showed the antimicrobial, antipregnancy, estrogenic, antitumor, antioxidant, and many other pharmacological activities. The article focus on traditional as well as modern use and various activities of the plant.
Cite this article:
Habeeba S. Shaikh, Siddiqua S. Shaikh. Babchi (Psoralea corylifolia): From a Variety of Traditional Medicinal Application to its Novel Roles in Various Diseases: A Review. Asian Journal of Pharmacy and Technology. 2021; 11(3):238-4. doi: 10.52711/2231-5713.2021.00039
Cite(Electronic):
Habeeba S. Shaikh, Siddiqua S. Shaikh. Babchi (Psoralea corylifolia): From a Variety of Traditional Medicinal Application to its Novel Roles in Various Diseases: A Review. Asian Journal of Pharmacy and Technology. 2021; 11(3):238-4. doi: 10.52711/2231-5713.2021.00039 Available on: https://ajptonline.com/AbstractView.aspx?PID=2021-11-3-9
REFERENCE:
1. Fransworth, N.R.; Akerele, O.; Bingel, A.S.; Soejarto, D.D.; Guo, Z. Medicinal plants in therapy. Bull. WHO 1985, 63, 965–981
2. Dev S, Nayak UR, Mehta G. Monoterpenoids- I, Psoralea corylifolia Linn. - Bakuchiol, A novel monoterpene phenol. Tetrahedron.1973; 29: 1119-1125.
3. Prasad NR, Anand C, Balasubramanian S, Pugalendi KV. Antidermatophytic activity of extracts from Psoralea corylifolia (Fabaceae) correlated with the presence of a flavonoid compound. Journal of Ethnopharmacology. 2004; 91: 21-24.
4. Tang SY, Whiteman M, Peng ZF, Jenner A, Yong EL, Halliwell B. Characterization of Antioxidant and Antiglycation properties and isolation of active ingredients from traditional chinese medicines. Free Radical Biology and Medicine. 2004; 36(12): 1575- 1587.
5. Haraguchi H, Inoue J, Tamura Y, Mizutani K. Inhibition of mitochondrial lipid peroxidation by Bakuchiol, a meroterpene from Psoralea corylifolia. Planta Medica 2000; 66(6): 569-71.
6. Pae HO, Cho H, Oh GS, Kim NY, Song EK, Kim YC, et al. Bakuchiol from Psoralea corylifolia inhibits the expression of inducible nitric oxide synthase gene via the inactivation of nuclear transcription factorkB in RAW 264.7 macrophages. International Journal of Immunopharmacology. 2001; 1: 1849-1855.
7. Qamaruddin A, Parveen N, Khan NU, Singhal KC. Potential antifilarial activity of the leaves and seeds extracts of Psoralea corylifolia on cattle filarial parasite Setariacervi. Journal of Ethnopharmacology. 2003; 84(2-3): 313.
8. Zhang CZ, Wang SX, Zhang Y, Chen JP, Liang XM. In vitro estrogenic activities of Chinese medicinal plants traditionally used for the management of menopausal symptoms. Journal of Ethnopharmacology. 2005; 98: 295-300.
9. Latha PG, Evans DA, Panikkar KR, Jayavardhanan KK. Immunomodulatory and antitumour properties of Psoralea corylifolia seeds. Fitoterapia. 2000; 71: 223–231.
10. Latha PG, Panikkar KR. Inhibition of chemical carcinogenesis by Psoralea corylifolia seeds. Journal of Ethnopharmacology. 1999; 68: 295-298.
11. Gidwani B, Alsapure RN, Duragkar NJ. Pharmacognostic and standardization and physico-chemical evaluation of Psoralea corylifolia linn seeds. Imperial J. Pharmacog. Natural Prod. 2011; 1: 145-151
12. Mishra S. Bhiashajya Ratnavali Chaukhambha Publication, Varanasi. Ed. 2009; (54): 302-310.
13. Mukherjee PK. Quality Control of Herbal Drugs. 1st ed, Business Horizon Pharmaceutical Publishers, pp. 600, 2002.
14. Rajpal V. Standardization of Botanicals, 2nd ed. Eastern Publisher, pp. 284, 2005.
15. Joshi SG (2000), Medicinal Plants, New Delhi: Oxford and IBH Publishing Co. Pvt. Ltd pp. 206–7.
16. Chopra RN, Chopra IC (1958), Indigenous Drugs of India; 2nd ed. Kolkata: Academic Publishers, pp. 391– 4.
17. Panda H (2000), Herbs, Cultivation and Medicinal Uses; New Delhi: National Institute of Industrial Research, pp. 479–81.
18. Zhao LH, Huang CY, Shan Z, Xiang BG and Mei LH. Fingerprint analysis of P. corylifolia by HLPC and LC-MS. J Chromatogr B. 2005; 821: 67–74.
19. Kaufman PB, Duke JA, Brielmann H, Boik J and Hoyt JE. A comparative survey of leguminous plants as sources of the isoflavones, genistein and daidzein: Implications for human nutrition and health. Journal of Alternative and Complementary Medicine.1997; 3(1): 7–12.
20. Fazelian M and Eslami B. In vitro antioxidant and free radical scavenging activity of Diospyros lotus and Pyrus boissieriana growing in Iran. Pharmacogn Mag. 2009; 5(18): 122–12
21. Buyukbalci A and Sedef Nehir EI. Determination of in vitro antidiabetic effects, antioxidant activities and phenol contents of some herbal teas. Plant Foods Hum Nutr. 2008; 63(1): 27–33.
22. Aslan M, Orhan N, Orhan DD and Ergun F. Hypoglycemic activity and antioxidant potential of some medicinal plants traditionally used in Turkey for diabetes. J Ethnopharmacol. 2010; 128(2): 384–389
23. Joshi N, Caputo GM, Weitekamp MR and Karchmer AW. Infections in Patients with Diabetes Mellitus. N Engl J Med. 199; 341(25): 1906–1912
24. Jeyakumar M, Jayabalan N. An efficient method for regeneration of plantletsfrom nodal explants of Psoralea corylifolia L. Plant. Cell Biotech. Mol. Biol. 2000; 1(1 and 2): 37.
25. Sun NJ, Woo SH, Cassady JM, Snapka RM. DNA polymerase and Topoisomerase II inhibitors from Psoralea corylifolia. J. Nat. prod. 1998; 61(3): 362-366.
26. Xiong Z, Wang D, Xu Y, Li F. Osteoblastic differentiation bioassay and its application to investigating the activity of fractions and compounds from Psoralea corylifolia L. Electronic J. 2003;58:925-928
27. Khushboo PS, Jadhav VM, Kadam VJ, and Sathe NS. P. corylifolia Linn. Kushtanashini. Pharmacogn Rev.2010; 4(7): 69–76
28. Agharkar SP. Medicinal Plants of Bombay Presidency; India: Scientific Publishers. 1991: 176–7
29. Sharma PC, Yelne MB and Dennis TJ (2001), Database on Medicinal Plants used in Ayurveda, New Delhi: Central Council for Research in Ayurveda and Siddha, Vol. 2, pp. 89–93
30. Ruan B, Kong LY, Takaya Y and Niwa M. Studies on chemical constituents of P. corylifolia L. J Asian Nat Prod Res. 2007; 9: 41–4
31. Lim SH, Ha TY, Ahn J and Kim S. Estrogenic activities of P. corylifolia L. seed extracts and main constituents. Phytomedicine. 2011; 18: 425–430
32. Krishnamurthi AK, Manjunath BL, Sastri BN, Deshaprabhu SB and Chadha YR. The Wealth of India: Raw Materials, New Delhi: CSIR. 1969; 7: 295–8.
33. Nadkarni KM (1976), Indian Materia Medica; Mumbai: Popular Prakashan Pvt. Ltd, Vol. 1, pp. 1019–22.
34. Sheng Y, Fan CQ, et al. Antibacterial prenylflavone derivatives from Psoralea corylifolia and their structure activity relationship.
35. Joshi SG (2000), Medicinal Plants, New Delhi: Oxford and IBH Publishing Co. Pvt. Ltd pp. 206–7
36. Chopra B, Dhingra AK, et al. Antimicrobial Activity of Psoralea corylifolia Linn. (Baguchi) Seeds Extracts by Organic Solvents and Supercritical Fluids. International Journal of Pharmaceutical and Clinical Research. 2013; 5(1): 13-16
37. Dwarampudi LP, Dhanabal SP, et al. Antipsoriatic activity and Cytotoxicity of ethanolic extract of Psoralia corylifolia seeds. Hygeia.J.D.Med. 2012; 4 (2): 41-48
38. Prasad R, Anandi C, Balasubramanian S, Pugalendi KV. Antidermatophytic activity of extracts from Psoralea corylifolia (fabaceae) correlated with the presence of a flavonoid compound. Journal of ethanopharmacology. 2004; 91: 21-24
39. Khatune NA, Islam ME., Rahman MAA. Baki MA., Gadik G. Haque ME., Pesticidal activity of a novel coumestan derivative isolated from psoralea corylifolia L. Against Tribolium casteneum Herbst. Adults and Larvae (coleptera: Tenebrionidae) Pakistan journal of agronomy. 2002; (4): 112-115.
40. Forestieri A M., Monfortre MT., Ragusa S. Trovato A, Lauk L., Antiinflammatory Analgesic and antipyretic activity in rodents of plant extract used in African Medicine, Phytother Res, 1996; 10 (2): 100-103.
41. Lim SH, Ha TY, Ahn J and Kim S. Estrogenic activities of P. corylifolia L. seed extracts and main constituents. Phytomedicine. 2011; 18: 425–430
42. Shilaskar DV, Parasar GC, “Studies on effect of psoralea corylifolia nd piper bettle on cholinesterase and succinil dehydrogenase. Enzymes as possible targets of their anthelmintic action” Planta Med. 2001, 62(7): 557-62
43. Borate A, Udgire M, et al “Antifungal Activity Associated with Psoralea corylifolia Linn. (Bakuchi) Seeds and Chemical Profile Crude Methanol Seed Extract” Mintage journal of Pharmaceutical and Medical Sciences, July– Sep. 2014, 3(3): 4-6
44. Jitpal K, Sharma S, Kumar S. In vivo Anti-diabetic and Anti-oxidant potential of Psoralea corylifolia seeds in streptozotocin induced type-2 Diabetic Rats. Jouranal of Health Science. 2011; 57(3): 225-235
45. Bhawya D, Kumar KR. Antioxidant, DNA damage and antibacterial effect of Psoralea corylifolia Asian journal of Pharmaceutical and clinicl Research. 2011; 4: 2011.
46. Sun NJ, Woo SH, Cassady JM, Snapka RM. DNA polymerase and Topoisomerase II inhibitors from Psoralea corylifolia. J. Nat. prod. 1998; 61(3): 362-366
47. Bhattacharji SK. Hand book of medicinal plants (painter publishers India), 1998; 287-288
48. Anusha S, Haja Sherief S, Sindhura S, Jaya Preethi P, Siva Kumar T. Synergistic effet of indigenous medicinal plant extracts on Psoriasis. International Journal of Phytopharmacy. 2013; 3(1): 23-29
49. Shilaskar DV, Parasar GC. Studies on effect of Psoralea corylifolia and piper bettle on cholinesterase and succinil dehydrogenase. Enzymes as possible targets of their anthelmintic action. planta med. 2001; 62(7): 557-62.
50. Wand D, Famei H, Jiang Z., Osteoblastic proliferation stimulatin activity of Psoralea corylifolia extracts and two of its flavonoids. International immunopharmacology. 2001; 1: 1849 –
51. Im AR, Chae SW, et al “Neuroprotective effects of Psoralea corylifolia Linn seed extracts on mitochondrial dysfunction induced by 3- nitropropionic acid” BMC Complementary and Alternative Medicine, 2014, 14: 370, 1-8
52. Takizawa T, Imai T, Mitsumori K, Takagi H, Onodera H, Yasuhara K, Ueda M, Tamura T and Hirose M (2002), Gonadal toxicity of an ethanol extract of P. corylifolia in a rat 90-day repeated dose study”, J Toxicol Sci, Vol. 27(2) pp.97-105
53. Xu Q, Pan Y, Yi LT, Li YC, Mo SF, Jiang FX, et al. (2008), “Antidepressant-like effects of psoralen isolated from P. corylifoliain the mouse forced swimming test”, Biol Pharm Bull, Vol.31, pp.1109–14.
54. Kim, D. W., Seo, K. H., Curtis‐Long, M. J., Oh, K. Y., Oh, J.‐W., Cho, J. K., …Park, K. H. (2014). Phenolic phytochemical displaying SARS‐CoVpapain‐like protease inhibition from the seeds of Psoralea corylifolia. Journal of Enzyme Inhibition and Medicinal Chemistry, 29(1), 59–63
55. Ling, F., Lu, C., Tu, X., Yi, Y., Huang, A., Zhang, Q., and Wang, G. (2013). Antiprotozoal screening of traditional medicinal plants: Evaluation of crude extract of Psoralea corylifolia against Ichthyophthirius multifiliisin goldfish. Parasitology Research,112(6), 2331–2340.
56. Chen, X., Yang, Y., and Zhang, Y. (2013). Isobavachalcone and bavachininfrom Psoraleae Fructus modulate Aβ42 aggregation process through different mechanisms in vitro. FEBS Letters,587(18), 2930–2935.
57. Behloul, N., and Wu, G. (2013). Genistein: A promising therapeutic agent for obesity and diabetes treatment. European Journal of Pharmacology, 698(1), 31–38
58. Asad, M., Razi, M., Sabih, D., Saqib, Q., Nasim, S., Murtaza, G., and Hussain, I. (2013). Anti‐venom potential of Pakistani medicinal plants: Inhibition ofanticoagulation activity of Naja naja karachiensis toxin. Cur. Sci, 105(10), 1419–1424
59. Latha, P. G., Evans, D. A., Panikkar, K. R., and Jayavardhanan, K. K. (2000). Immunomodulatory and antitumour properties of Psoralea corylifolia seeds. Fitoterapia, 71(3), 223–231
60. Jeong, D., Watari, K., Shirouzu, T., Ono, M., Koizumi, K., Saiki, I., Miyamoto, T. (2013). Studies on lymphangiogenesis inhibitors fromKorean and Japanese crude drugs. Biological and Pharmaceutical Bulle-tin,36(1), 152–157
61. Nam SW, Baek JT, Lee DS, Kang SB, Ahn BM and Chung KW (2005), “A case of acute cholestatic hepatitis associated with the seeds of P. corylifolia (BohGol-Zhee)”, Clin Toxicol (Phila), Vol. 43(6), pp. 589- 91.
62. Toyooka, T., and Ibuki, Y. (2009). Histone deacetylase inhibitor sodium buty-rate enhances the cell killing effect of psoralen plus UVA by attenuatingnucleotide excision repair. Cancer Research,69(8), 3492–3500.
63. Jing, H., Wang, S., Wang, M., Fu, W., Zhang, C., and Xu, D. (2017). Isobavachalcone attenuates MPTP‐induced Parkinson's disease in miceby inhibition of microglial activation through NF‐κB pathway. PLoS One,12(1), e0169560