Author(s):
Lingesh Kumar MS, Oyitabu Ifunanya Mercy, Nayana DN1, Shreya K, J Baseer UL Sumeer, Vemula Kusum Devi, Vijaya G Joshi, CSR Lakshmi, Rama Bukka, Rama Nargund, Shravan L Nargund, Shachindra L. Nargund, Malviya Nidhi
Email(s):
nidhi.malviya7@gmail.com
DOI:
10.52711/2231-5713.2026.00008 
Address:
Lingesh Kumar MS1, Oyitabu Ifunanya Mercy1, Nayana DN1, Shreya K1, J Baseer UL Sumeer1, Vemula Kusum Devi2, Vijaya G Joshi3, CSR Lakshmi1, Rama Bukka1, Rama Nargund5, Shravan L Nargund1, Shachindra L. Nargund4, Malviya Nidhi1
1Department of Pharmaceutics, Nargund College of Pharmacy, Bangalore - 85, Karnataka, India.
2Department of Pharmaceutics, NITTE College of Pharmaceutical Sciences, Bangalore – 64, India.
3Department of Pharmaceutics, Government College of Pharmacy, Bangalore - 27, Karnataka, India.
4Department of Pharmachemistry, Nargund College of Pharmacy, Bangalore - 85, Karnataka, India.
5Department of Pharmacology, Nargund College of Pharmacy, Bangalore - 85, Karnataka, India.
*Corresponding Author
Published In:
Volume - 16,
Issue - 1,
Year - 2026
ABSTRACT:
Niosomes were introduced as an alternative to traditional colloidal drug carriers such as emulsions, liposomes, and polymer-based systems. Niosomes offer enhanced stability, biocompatibility, and controlled drug release while overcoming limitations of conventional carriers. Niosomes are vesicular drug carriers composed of non-ionic surfactants, providing targeted and sustained drug release. The article explores strategies to minimize adverse effects using optimized manufacturing methods like thin-film hydration, reverse phase evaporation, and microfluidization. Advanced analytical techniques like electron microscopy, dynamic light scattering, and nuclear magnetic resonance are employed to characterize niosomes. This study evaluates niosome production techniques, drug loading efficiency, encapsulation ability, and controlled release properties, with a particular focus on drug delivery mechanisms. Topical niosomal gels are developed to enhance drug permeation, stability, and therapeutic efficacy. While conventional gels suffer from poor skin permeability, potential allergic reactions, and limited plasma drug concentration, niosomes improve drug retention, prevent enzymatic degradation, and develop penetration of larger molecules. This study highlights the possibility of niosomes as a potential drug delivery system for topical and systemic applications
Cite this article:
Lingesh Kumar MS, Oyitabu Ifunanya Mercy, Nayana DN1, Shreya K, J Baseer UL Sumeer, Vemula Kusum Devi, Vijaya G Joshi, CSR Lakshmi, Rama Bukka, Rama Nargund, Shravan L Nargund, Shachindra L. Nargund, Malviya Nidhi. Niosome: A Comprehensive Review of Development, Characterization and Applications. Asian Journal of Pharmacy and Technology. 2026; 16(1):45-1. doi: 10.52711/2231-5713.2026.00008
Cite(Electronic):
Lingesh Kumar MS, Oyitabu Ifunanya Mercy, Nayana DN1, Shreya K, J Baseer UL Sumeer, Vemula Kusum Devi, Vijaya G Joshi, CSR Lakshmi, Rama Bukka, Rama Nargund, Shravan L Nargund, Shachindra L. Nargund, Malviya Nidhi. Niosome: A Comprehensive Review of Development, Characterization and Applications. Asian Journal of Pharmacy and Technology. 2026; 16(1):45-1. doi: 10.52711/2231-5713.2026.00008 Available on: https://ajptonline.com/AbstractView.aspx?PID=2026-16-1-8
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