Author(s): Sushil D. Patil, Bhavini D. Chande, Kirti M. Budukhale, Radhika V. Damare, Nilam Kale, Shivangi S. Pathak

Email(s): sushilpharma@rediffmail.com

DOI: 10.5958/2231-5713.2018.00014.4   

Address: Prof. Sushil D. Patil*, Bhavini D. Chande, Kirti M. Budukhale, Radhika V. Damare, Nilam Kale, Shivangi S. Pathak
Department of Pharmaceutical Chemistry, MET's Institute of Pharmacy, Bhujbal Knowledge City, Adgaon Nashik, Maharashtra, India.
*Corresponding Author

Published In:   Volume - 8,      Issue - 2,     Year - 2018


ABSTRACT:
Present investigation was to develop novel formulation methanolic extract of Ixora coccinea leaves (ICF-ME), which is reported to possess Anti-oxidant activityanti-bacterial activitiesandantimicrobial activity. Ixora coccinea formulation showed significant activities antibacterial andantioxidant assays compared to the standardantioxidant in a dose dependent manner andremarkable activities to scavenge reactive oxygen species (ROS). Staphylococcus aureus and E. coli was evaluated by the standard cup plate method and the inhibition zone diameters were measured for antibacterial activity. It is evident that formulation F-4 containing both clove oil (0.7%) and Ixora coccinea (7%) showed larger zone of inhibition in comparison to other formulations.So antibacterial and antioxidant activity of formulation F-4 found to be superior to other formulations. Results of all other evaluation parameters of F-4 were also satisfactory among all the formulations.


Cite this article:
Sushil D. Patil, Bhavini D. Chande, Kirti M. Budukhale, Radhika V. Damare, Nilam Kale, Shivangi S. Pathak. Evaluation Ixora coccinea Formulation for antibacterial and antioxidant activity. Asian J. Pharm. Tech. 2018; 8 (2):88-91. doi: 10.5958/2231-5713.2018.00014.4


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DOI: 10.5958/2231–5713 


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