Extraction, Isolation and Characterization of Okra Mucilage, as Potential source of Binder in Tablet

Rutuja R Shah; Rahul S Adnaik; Pratibha R Adnaik; Swapnil S Patil

doi:10.52711/2231-5713.2023.00032

Asian Journal of Pharmacy and Technology

ISSN

2231-5713 (Online)
2231-5705 (Print)

Submit Article

Extraction, Isolation and Characterization of Okra Mucilage, as Potential source of Binder in Tablet

Author(s): Rutuja R Shah, Rahul S Adnaik, Pratibha R Adnaik, Swapnil S Patil

Email(s): Shaha.rutu@gmail.com

DOI: 10.52711/2231-5713.2023.00032

Address: Rutuja R Shah, Rahul S Adnaik, Pratibha R Adnaik, Swapnil S Patil
Anandi B Pharmacy College, Kalambe Tarf Kale.
*Corresponding Author

Published In: Volume - 13, Issue - 3, Year - 2023

View HTML

Purchase PDF

ABSTRACT:
The major objective of the present investigation was to extract a natural polymer (okra mucilage) with its characterization as a pharmaceutical binder and to formulate, develop and evaluate the compression of tablet using okra binder. Binders are agent employed to impart cohesiveness to the granules. This ensures the tablet remain intact after compression. The researcher is trying to find new excipient for potential use of binding agent in tablet formulation continues to the interest. This is because different binding agent can be useful in achieving various tablet mechanical strength and drug release properties for different pharmaceutical purpose. The result presented here shows that the mucilage obtained from okra can be used as a binder in paracetamol tablets formulation with good physical properties. Tablet of long disintegration times were produced, hence it’s potential in binding and prepare the granule of pharmaceutical formulation.

Keywords:

Cite this article:
Rutuja R Shah, Rahul S Adnaik, Pratibha R Adnaik, Swapnil S Patil. Extraction, Isolation and Characterization of Okra Mucilage, as Potential source of Binder in Tablet. Asian Journal of Pharmacy and Technology. 2023; 13(3):178-2. doi: 10.52711/2231-5713.2023.00032

Cite(Electronic):
Rutuja R Shah, Rahul S Adnaik, Pratibha R Adnaik, Swapnil S Patil. Extraction, Isolation and Characterization of Okra Mucilage, as Potential source of Binder in Tablet. Asian Journal of Pharmacy and Technology. 2023; 13(3):178-2. doi: 10.52711/2231-5713.2023.00032 Available on: https://ajptonline.com/AbstractView.aspx?PID=2023-13-3-5

REFERENCE:
1.   Suhailah H et al, Anticancer activity of okra raw polysaccharides extracts against human liver cancer cells, Tropical Journal of Pharmaceutical Research (2019)18 (8): 1667-1672
2.   Mark L. Woolfe .et al, Studies on the Mucilage Extracted from Okra Fruits (Hibiscus esculentus L.) and Baobab Leaves (Adansonia digitata L.), J. Sci. Fd Agric. (2018)1917(28),519-529.
3.   Noorlaila A et al, Emulsifying properties of extracted Okra (Abelmoschus esculentus L.) mucilage of different maturity index and its application in coconut milk emulsion, International Food Research Journal, (2015)22(2): 782-787
4.   Ahiakpa J.K. et al, Mucilage Content of 21 Accessions of Okra (Abelmoschus spp L.), Scientia Agricultural, (2014) 2 (2): 96-101
5.   Leonardo G. M et al, Lectin of Abelmoschus esculentus (okra) promotes selective antitumor effects in human breast cancer cells, Biotechnol Lett (2014) 36:461–469
6.   Rishabha M. et al, Extraction Characterization and Evaluation of Selected Mucilage as Pharmaceutical Excipient, PHARMACEUTICAL EXCIPIENT, (2011)39-43
7.   Ameena K et al, Isolation of the mucilage from Hibiscus rosasinensis Linn. and Okra (Abelmoschus esculentus Linn.) and studies of the binding effects of the mucilage, Asian Pacific Journal of Tropical Medicine, (2010)539-543.
8.   Pranati S. et al, formulation and evaluation of paracetamol tablet, international journal of pharmaceutical science review and research, volume 3, issue 1, July – august 2010, article 006.
9.   Habtamu F. et al, Nutritional quality and health benefit of okra (abelmoschus esculentus L.) a review, international journal of nutrition and food science 2015. 4(2): 208-215.

Asian Journal of Pharmacy and Technology (AJPTech.) is an international, peer-reviewed journal, devoted to pharmaceutical sciences...... Read more >>>

RNI: Not Available
DOI: 10.5958/2231–5713