Author(s): Bandagisa Fouziya, Hindustan Abdul Ahad, Dontha Swamy Charan, Jagarlamudi Sri Vidya, Ummadi Chandana Reddy, Puli Nandini Reddy

Email(s): abdulhindustan@gmail.com

DOI: 10.52711/2231-5713.2022.00018   

Address: Bandagisa Fouziya1, Hindustan Abdul Ahad2*, Dontha Swamy Charan1, Jagarlamudi Sri Vidya1, Ummadi Chandana Reddy1, Puli Nandini Reddy1
1Nirmala College of Pharmacy, Chennai - Hyderabad Bypass Road, Ukkayapalli, Kadapa - 516002, AP, India.
2Department of Industrial Pharmacy, Raghavendra Institute of Pharmaceutical Education and Research (RIPER)-Autonomous, Ananthapuramu, Andhra Pradesh, India.
*Corresponding Author

Published In:   Volume - 12,      Issue - 2,     Year - 2022


ABSTRACT:
The authors aimed to create and characterise Cefpodoxime Proxetil (CDP) niosomes with site-specific delivery in order to minimise disruptions in gastric disintegration and absorption and achieve the desired therapeutic response. CDP niosomes were created using an Ether injection process with a variety of CDP, cholesterol, and Sorbitans concentrations (Span 40, 60 and 80). Compatibility studies with the excipients used, vesicular shape, size, entrapment efficiency, drug content, and in-vitro drug release were all performed on the fabricated niosomes. The results revealed that the primed niosomes pass and satisfy all physicochemical characterizations performed. The study concludes that CDP can be formulated as niosomes by ether injection techniques for enhanced absorption of drug.


Cite this article:
Bandagisa Fouziya, Hindustan Abdul Ahad, Dontha Swamy Charan, Jagarlamudi Sri Vidya, Ummadi Chandana Reddy, Puli Nandini Reddy. Fabrication and Evaluation of Cefpodoxime Proxetil Niosomes. Asian Journal of Pharmacy and Technology. 2022; 12(2):109-2. doi: 10.52711/2231-5713.2022.00018

Cite(Electronic):
Bandagisa Fouziya, Hindustan Abdul Ahad, Dontha Swamy Charan, Jagarlamudi Sri Vidya, Ummadi Chandana Reddy, Puli Nandini Reddy. Fabrication and Evaluation of Cefpodoxime Proxetil Niosomes. Asian Journal of Pharmacy and Technology. 2022; 12(2):109-2. doi: 10.52711/2231-5713.2022.00018   Available on: https://ajptonline.com/AbstractView.aspx?PID=2022-12-2-4


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4.    Ahad HA, Rani EM, Kranthi G, Gupta PR, Reddy MN, Prakash G. Spectrophotometric Determination of Cefadroxil in Cefadroxil Tablets by Bromination Method. Analytical Chemistry Letters. 2011; 1(2): 185-8.
5.    Ahad HA, Sreenivasulu R, Mallapu Rani E, Reddy BV. Preparation and evaluation of famotidine high density gastro retentive microspheres with synthetic and natural polymers. Journal of Pharmaceutical Education and Research. 2011; 2(1).
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