Author(s): Rohan Patil, Neha Patil, Aniket Patil, S. J. Shid, V.N. Dange, C.S. Magdum, S.K. Mohite

Email(s): Shubhangishid@gmail.com

DOI: 10.5958/2231-5713.2016.00026.X   

Address: Rohan Patil, Neha Patil, Aniket Patil , S. J. Shid, V.N. Dange, C.S. Magdum, S.K. Mohite
Department of Pharmaceutics, Rajarambapu College of Pharmacy, Kasegaon, Tal- Walwa, Dist- Satara
*Corresponding Author

Published In:   Volume - 6,      Issue - 3,     Year - 2016


ABSTRACT:
Novel drug delivery system assists to achieve better patient compliance. Fast dissolving tablets are one of them. FDT have benefits such as accurate dosing, easy portability and manufacturing, good physical and chemical stability and an ideal alternative for pediatric and geriatric patients. FDDT formulation combines the advantage of both liquid and conventional tablet formulation while also offering advantage over both traditional dosage forms. This review gives a view of advantages, limitations, need for formulating FDTS, Formulation factors, excipients used, and methodology and evaluation parameters. Fast dissolving tablets (FDTs) can be prepared by different methods, such as direct compression, freeze-drying, spray drying, sublimation, wet granulation method4. The basic approach for the development of FDTs is the use of superdisintegrants. The aim of this study was to formulate FDTs with sufficient mechanical integrity and to achieve faster disintegration in the oral cavity without water. To achieve this goal, mannitol used as diluent as well as sweetening agent for the formulation of tablets. Attempts were made to enhance dissolution rate along with faster disintegration using superdisintegrants, like microcrystalline cellulose. Tramadol hydrochloride, a centrally acting synthetic opioid analgesic, was selected as the active pharmaceutical ingredient in the study.


Cite this article:
Rohan Patil, Neha Patil, Aniket Patil , S. J. Shid, V.N. Dange, C.S. Magdum, S.K. Mohite. Preparation and Evaluation of Fast Dissolving Tablet Tramadol Hydrochloride. Asian J. Pharm. Tech. 2016; 6 (3): 183-185. doi: 10.5958/2231-5713.2016.00026.X


Recomonded Articles:

Author(s): Hafsa, Asfa, Nuha Rasheed, Abdul Saleem Mohammad

DOI: 10.5958/2231-5713.2017.00001.0         Access: Open Access Read More

Author(s): Juveriya Fatima, Saniya Khan, Nuha Rasheed, Abdul Saleem Mohammad

DOI: 10.5958/2231-5713.2017.00009.5         Access: Open Access Read More

Author(s): Avinash B. Thalkari, Pawan N. Karwa, Chandrakant S. Gawli

DOI: 10.5958/2231-5713.2018.00017.X         Access: Open Access Read More

Author(s): Safa Mohammed Sadiq, Amtul Kareem, Nuha Rasheed, Abdul Saleem Mohammad

DOI: 10.5958/2231-5713.2017.00002.2         Access: Open Access Read More

Author(s): Abhijit Ray

DOI:         Access: Open Access Read More

Author(s): Abhishek K. Sah, Manmohan Singh Jangdey, Sanjay J. Daharwal

DOI:         Access: Open Access Read More

Author(s): Manohar D. Kengar, Rohit S. Howal, Dattatray B. Aundhakar, Amit V. Nikam, Priyajit S. Hasabe

DOI: 10.5958/2231-5713.2019.00010.2         Access: Closed Access Read More

Author(s): Abdul Saleem Mohammad, Swetha Devidi, Nikhat Fatima, Humera Badar, Syeda Saba Sulthana, Mohammad Akthar Sulthana, Nuha Rasheed

DOI:         Access: Open Access Read More

Author(s): Yogita. Chowdhary

DOI: 10.5958/2231-5713.2018.00002.8         Access: Open Access Read More

Author(s): Brijesh Kumar Duvey, Rohit Goyel, Bharat Parashar, Denesh Verma, Hitesh Dhameja, Dharmesh Sharma

DOI:         Access: Open Access Read More

Author(s): Vishwas R. Potphode, Amol S. Deshmukh, Vijay R. Mahajan

DOI:         Access: Open Access Read More

Author(s): P. Swathi, K. Rajeswar Dutt, K. N. V Rao, M. Alagar Raja

DOI: 10.5958/2231-5713.2017.00025.3         Access: Open Access Read More

Author(s): Anju govind, Manjunath B Menden, Ravikumar, Simila1, Mercy, Narayana Swamy VB

DOI: 10.5958/2231-5713.2016.00013.1         Access: Open Access Read More

Author(s): Rana Khan, Aizaz Ahmed Khan, Nuha Rasheed, Abdul Saleem Mohammad

DOI: 10.5958/2231-5713.2017.00012.5         Access: Open Access Read More

Author(s): Nirmala Rangu, B. Chaitanya Kumari, Ganesh Akula, A Jaswanth

DOI: 10.5958/2231-5713.2018.00001.6         Access: Open Access Read More

Author(s): Rohan Patil, Neha Patil, Aniket Patil , S. J. Shid, V.N. Dange, C.S. Magdum, S.K. Mohite

DOI: 10.5958/2231-5713.2016.00026.X         Access: Open Access Read More

Author(s): Neha Srivastava, Seema Thakur, Anchal Bajaj, Nikita Sahi

DOI:         Access: Open Access Read More

Asian Journal of Pharmacy and Technology (AJPTech.) is an international, peer-reviewed journal, devoted to pharmaceutical sciences...... Read more >>>

RNI: Not Available                     
DOI: 10.5958/2231–5713 


Recent Articles




Tags