Author(s):
Purvesh H. Patil, Azam Z. Shaikh
Email(s):
purveshppatill02@gmail.com
DOI:
10.52711/2231-5713.2025.00039
Address:
Purvesh H. Patil1, Azam Z. Shaikh2
1Student, Department of Pharmaceutics, P.S.G.V.P Mandal’s College of Pharmacy, Shahada, Nandurbar.
2Assistant Professor, Department of Pharmaceutics, P.S.G.V.P Mandal’s College of Pharmacy, Shahada, Nandurbar.
*Corresponding Author
Published In:
Volume - 15,
Issue - 3,
Year - 2025
ABSTRACT:
The purpose and aim of this study is to create a new herbal gel formulation for the treatment of fungal infections by combining powdered extracts of Tulsi (Ocimum sanctum Linn) and betel (Piper betle) leaves. Using a standardized process, the gel formulation was created, and its in vitro antifungal effectiveness against common fungal diseases was assessed along with its pH, viscosity, spreadability, and drug concentration. The second test assessed the dosage forms' physical attributes, such as their viscosity, adhesion, dispersion, pH, and organoleptic qualities. The Mann-Whitney method was used to examine this data, and the conclusion was removed from providing a quantitative description of the findings. The findings showed that the herbal gel had notable antifungal action and appealing physical properties, indicating that it might be used as a substitute for conventional treatments for fungal infections. Its effectiveness and safety in human beings need to be confirmed by more clinical research.
Cite this article:
Purvesh H. Patil, Azam Z. Shaikh. The Formulation and Evaluation of a Herbal Gel contains powdered extracts of Tulsi leaves (Ocimum sanctum Linn) and Betel leaves (Piper betle) for the treatment of Fungal Infections. Asian Journal of Pharmacy and Technology. 2025; 15(3):256-0. doi: 10.52711/2231-5713.2025.00039
Cite(Electronic):
Purvesh H. Patil, Azam Z. Shaikh. The Formulation and Evaluation of a Herbal Gel contains powdered extracts of Tulsi leaves (Ocimum sanctum Linn) and Betel leaves (Piper betle) for the treatment of Fungal Infections. Asian Journal of Pharmacy and Technology. 2025; 15(3):256-0. doi: 10.52711/2231-5713.2025.00039 Available on: https://ajptonline.com/AbstractView.aspx?PID=2025-15-3-7
REFERENCE:
1. Dixon DM, McNeil MM, Cohen ML, et al. Fungal infections: a growing Threat. Public Health Rep. 1996; 111(3): 226–235.
2. Chian–Yong Low, Coleman Rotstein. Emerging fungal infections in immune–compromisedpatients. F1000 Med Rep. 2011; 3:14.
3. Pradip Debnath. Chemistry behind the Betel leaves, Betel Quid: Their Health Benefits and adverse health Effect. 2021;2-3.
4. Joshi, B., Sah, G. P., Basnet, B. B., Bhatt, M. R., Sharma, D., Subedi, K, and Malla, R. Phytochemical extractionand antimicrobial properties of different medicinal plants: Ocimum sanctum (Tulsi), Eugenia caryophyllata (Clove), Achyranthesbidentata (Datiwan) and Azadirachta indica (Neem). Journal of Microbiology and Antimicrobials. 2011; 3(1): 1-7
5. Mohsin J. Jamadar. Research Article Journal of Pharmaceutical Research and Education. 2017; 1(2): 201- 224
6. S´anchez E, Heredia N, Garcıa S. Extracts of edible and Medicinal plants damage membranes of Vibrio cholerae. Appl Environ Microbiol. 2010; 76: 6888-6894.
7. Das S, Haldar PK, Pramanik G. Formulation and Evaluation of herbal gel containing Clerodendronin fortunatum Leaf Extract. Int J Pharm Tech Res. 2011; 1: 140-143.
8. Mohsin. J. Jamadar. Preparation and Evaluation of Herbal Gel Formulation. 2017
9. Mokashi M. Formulation and of Herbal Gel Containing Methanolic Extract of Annona squamosa Leaves. Int J Sci Res. 2015; 4: 1064-1065.
10. Thombre KP, Sharma D, Lanjewar AM. Formulation and evaluation pharmaceutical aqueous gel of powdered cordia Dichotoma leaves with guava leaves. Am J Pharm Tech Res. 2018; 8: 269-274.
11. Yogi D. Formulation and evaluation of gel containing Amlexanox for mouth ulcer. Int J Appl Pharm. Biol Res. 2015; 4: 356-364.
12. Kaur LP, Garg R, Gupta GD. Development and evaluation of topical gel of minoxidil from different polymer bases in application of alopecia. Int J Pharmacy Pharm Sci. 2010; 2: 43-47.
13. Mendhekar SY, Thorat PB, Bodke NN, Jadhav SL. Formulation and evaluation of gel containing Neem, Turmeric, Aloevera, Green tea and Lemon extract with Activated charcoalAndhoney. Eur J Pharmaand Med Res. 2017; 4: 439-444.
14. Brookfield Engineering Labs., Inc., Brookfield Viscometer; type DV- II+PRO Instruction manual, Manual No. M03-165-E0211; 2015. P. 5-23.
15. Pandey N. Formulation and evaluation of invitro antimicrobial activity of gel containing oils and of polymer on their antimicrobial activity. Int J Pharm and Pharmaceutical Science. 2011; 3: 234-238.
16. Chauhan K, Tyagi B, Singh B and Agarwal S. Accelerated stability studies of polyherbal preparation (Ezmov) capsule. 1999; 18(3and4): 210- 217.
17. Rathee J. S., Patro B.S., Mula S., Gamre S., And Chattopadhyay S. Antioxidant Activity of Piper betel Leaf Extract and Its Constituents. J. Agric. Food Chem. 2006; 54 (24): 9046–9054.