Gold Nanoparticle-Small Drug Molecule Conjugates: Therapeutic Applications and Benefits as Compared to Free Drug

Pravin Kumar; Mahendra Singh Ashawat; Vinay Pandit

doi:10.5958/2231-5713.2018.00009.0

Asian Journal of Pharmacy and Technology

ISSN

2231-5713 (Online)
2231-5705 (Print)

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Gold Nanoparticle-Small Drug Molecule Conjugates: Therapeutic Applications and Benefits as Compared to Free Drug

Author(s): Pravin Kumar, Mahendra Singh Ashawat, Vinay Pandit

Email(s): kumar3785@gmail.com

DOI: 10.5958/2231-5713.2018.00009.0

Address: Pravin Kumar, Mahendra Singh Ashawat, Vinay Pandit
Department of Pharmaceutics, Laureate Institute of Pharmacy, Kangra, H. P, India-177101
*Corresponding Author

Published In: Volume - 8, Issue - 1, Year - 2018

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ABSTRACT:
Gold nanoparticles (AuNPs) have been profoundly investigated for drug delivery applications. Various widely used small drugs molecules when conjugated either covalently or non-covalently with the AuNPs, showed improved therapeutic effect with reduced dose and adverse effects as compared to drug alone. This review focuses on therapeutic efficiency of AuNPs-small drug molecule conjugates as anti-cancer, anti-bacterial, anti-retroviral and anti-arthritic agents. The basic approaches of conjugation, brief of procedure followed for activity determination and mechanism of action of conjugates have also been discussed.

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Cite this article:
Pravin Kumar, Mahendra Singh Ashawat, Vinay Pandit. Gold Nanoparticle-Small Drug Molecule Conjugates: Therapeutic Applications and Benefits as Compared to Free Drug. Asian J. Pharm. Tech. 2018; 8 (1): 52-62. doi: 10.5958/2231-5713.2018.00009.0

Cite(Electronic):
Pravin Kumar, Mahendra Singh Ashawat, Vinay Pandit. Gold Nanoparticle-Small Drug Molecule Conjugates: Therapeutic Applications and Benefits as Compared to Free Drug. Asian J. Pharm. Tech. 2018; 8 (1): 52-62. doi: 10.5958/2231-5713.2018.00009.0 Available on: https://ajptonline.com/AbstractView.aspx?PID=2018-8-1-9

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DOI: 10.5958/2231–5713