Author(s):
Pravin Kumar, Mahendra Singh Ashawat, Vinay Pandit
Email(s):
kumar3785@gmail.com
DOI:
10.5958/2231-5713.2018.00009.0 
Address:
Pravin Kumar, Mahendra Singh Ashawat, Vinay Pandit
Department of Pharmaceutics, Laureate Institute of Pharmacy, Kangra, H. P, India-177101
*Corresponding Author
Published In:
Volume - 8,
Issue - 1,
Year - 2018
ABSTRACT:
Gold nanoparticles (AuNPs) have been profoundly investigated for drug delivery applications. Various widely used small drugs molecules when conjugated either covalently or non-covalently with the AuNPs, showed improved therapeutic effect with reduced dose and adverse effects as compared to drug alone. This review focuses on therapeutic efficiency of AuNPs-small drug molecule conjugates as anti-cancer, anti-bacterial, anti-retroviral and anti-arthritic agents. The basic approaches of conjugation, brief of procedure followed for activity determination and mechanism of action of conjugates have also been discussed.
Cite this article:
Pravin Kumar, Mahendra Singh Ashawat, Vinay Pandit. Gold Nanoparticle-Small Drug Molecule Conjugates: Therapeutic Applications and Benefits as Compared to Free Drug. Asian J. Pharm. Tech. 2018; 8 (1): 52-62. doi: 10.5958/2231-5713.2018.00009.0
Cite(Electronic):
Pravin Kumar, Mahendra Singh Ashawat, Vinay Pandit. Gold Nanoparticle-Small Drug Molecule Conjugates: Therapeutic Applications and Benefits as Compared to Free Drug. Asian J. Pharm. Tech. 2018; 8 (1): 52-62. doi: 10.5958/2231-5713.2018.00009.0 Available on: https://ajptonline.com/AbstractView.aspx?PID=2018-8-1-9