Author(s): Kalpak Gajbhiye, Nawaz Hakam, Gauri Rathod, Mukund Tawar

Email(s): gajbhiyekalpak@gmail.com

DOI: 10.52711/2231-5713.2021.00034   

Address: Kalpak Gajbhiye*, Nawaz Hakam, Gauri Rathod, Mukund Tawar
Department of Pharmaceutics, P.R. Pote College of Pharmacy, Kathora Road, Amravati – 444604 Maharashtra, India.
*Corresponding Author

Published In:   Volume - 11,      Issue - 3,     Year - 2021


ABSTRACT:
The present research was designed to evaluate matrix type Benidipine Hydrochloride transdermal patches. So, the present work is an attempt to study effect of variation in Methocel E15LV concentration and study effect of hydrophilic and hydrophobic Methocel E15LV and Eudragit RL100 combination on release profile of Benidipine Hydrochloride. All prepared formulations were evaluated for physical and mechanical properties like thickness, moisture uptake, percent flatness, tensile strength, and percent elongation. An attempt was made to get a patch with suitable drug release property as well as physical and mechanical properties. A formulation containing Methocel E15LV 2% has shown good physical, mechanical and in-vitro drug release properties. It also showed good diffusion of Benidipine Hydrochloride across goat skin.


Cite this article:
Kalpak Gajbhiye, Nawaz Hakam, Gauri Rathod, Mukund Tawar. Formulation and Evaluation of Transdermal Patches of Benidipine Hydrochloride. Asian Journal of Pharmacy and Technology 2021; 11(3):207-2. doi: 10.52711/2231-5713.2021.00034

Cite(Electronic):
Kalpak Gajbhiye, Nawaz Hakam, Gauri Rathod, Mukund Tawar. Formulation and Evaluation of Transdermal Patches of Benidipine Hydrochloride. Asian Journal of Pharmacy and Technology 2021; 11(3):207-2. doi: 10.52711/2231-5713.2021.00034   Available on: https://ajptonline.com/AbstractView.aspx?PID=2021-11-3-4


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