Author(s): Mayur R. Bhurat, S. D. Barhate

Email(s): bhuratmayur@gmail.com

DOI: 10.5958/2231-5713.2015.00005.7   

Address: Mayur R. Bhurat1,2*and Dr. S. D. Barhate1
1Shree Sureshdada Jain Institute of Pharmaceutical Education and Research, Jammer 2J.J.T. University, Zunzunu, Rajasthan
*Corresponding Author

Published In:   Volume - 5,      Issue - 1,     Year - 2015


ABSTRACT:
Remusatia vivipara is a common herbaceous belongs to the family of Araceae. Tubers of plant contain mucilage hence attempt to evaluate the tubers for suitability as tablet binder is considered and the present investigation repots the isolation of mucilage of Remusatia vivipara tubers. The DSC and FTIR thermograms of drug and mucilage indicated no chemical interaction. Phytochemical and Physiochemical characteristics of mucilage were studied which confirmed the mucilage nature. The mucilage was evaluated for its granulating and binding properties in compressed tablet using Metformin HCl as model drug. The granules prepared by mucilage with different concentration such as 1%, 3%, 5% and 10% were compared with starch paste, which was used as standard binder. The tablets had good physiochemical properties and the drug release was more than 95% within 24hr. It was observed that decreasing the concentration of mucilage increases hardness and the disintegration time. The tablet prepared using 1% and 3% shows drug release rate in sustained manner and that of standard binder 10% starch paste used for comparison. Remusatia vivipara mucilage could be used as a good binding agent at very low concentrations. This can be used for sustaining the drug release from tablets, since the prepared tablets produced a sticky film of hydration on the surface, which ultimately reduces drug release rate and hence it can be evaluated for its efficacy to sustain the drug release.


Cite this article:
Mayur R. Bhurat, S. D. Barhate. Evaluation of Binding Property of Remusatia vivipara (Roxb) Mucilage in Tablet Formulation. Asian J. Pharm. Tech. 2015; Vol. 5: Issue 1, Pg 23-28. doi: 10.5958/2231-5713.2015.00005.7


Recomonded Articles:

Author(s): Hafsa, Asfa, Nuha Rasheed, Abdul Saleem Mohammad

DOI: 10.5958/2231-5713.2017.00001.0         Access: Open Access Read More

Author(s): Yogita. Chowdhary

DOI: 10.5958/2231-5713.2018.00002.8         Access: Open Access Read More

Author(s): Beedha. Saraswathi, Dr. T. Satyanarayana, K. Mounika, G. Swathi , K. Sravika, M. Mohan Krishna

DOI: 10.5958/2231-5713.2018.00004.1         Access: Open Access Read More

Author(s): Nirmala Rangu, B. Chaitanya Kumari, Ganesh Akula, A Jaswanth

DOI: 10.5958/2231-5713.2018.00001.6         Access: Open Access Read More

Author(s): Rohan Patil, Neha Patil, Aniket Patil , S. J. Shid, V.N. Dange, C.S. Magdum, S.K. Mohite

DOI: 10.5958/2231-5713.2016.00026.X         Access: Open Access Read More

Author(s): Abhishek S. Pujari, Nitin A. Gaikwad, Indrajeet V. Mane, Ganesh B. Vambhurkar, Pravin P. Honmane

DOI: 10.5958/2231-5713.2018.00019.3         Access: Open Access Read More

Author(s): Jenifer. P, C.P. Balakrishnan, S. Chidambaram Pillai

DOI: 10.5958/2231-5713.2017.00018.6         Access: Open Access Read More

Author(s): Neha Srivastava, Seema Thakur, Anchal Bajaj, Nikita Sahi

DOI:         Access: Open Access Read More

Author(s): Basavaraj, Someswara Rao B, S.V Kulkarni, Pramod Patil , Chetan Surpur

DOI:         Access: Open Access Read More

Author(s): Pawar P.B., M.P. Wagh, S.N. Bhandare

DOI:         Access: Open Access Read More

Author(s): Madan Singh, Prashant Soni, Neeraj Upmanyu , Yogesh Shivhare

DOI:         Access: Open Access Read More

Author(s): Godbole Ajeet Madhukar, Patel Bhautik V, Somnache Sandesh Narayan, Prajapati Ashish R, Yadav Pradeep

DOI: 10.5958/2231-5713.2017.00004.6         Access: Open Access Read More

Author(s): Vaishali B. Morade, Vandana R. Daga, Dr. Prashant R. Malpure

DOI: DOI: 10.5958/2231-5713.2018.00006.5         Access: Open Access Read More

Author(s): Dange YD, Honmane SM, Patil PA, Gaikwad UT, Jadge DR

DOI: 10.5958/2231-5713.2017.00010.1         Access: Open Access Read More

Author(s): Sarfaraz Md., Arshad Ahmed Khan K., Doddayya H., Reddy S.R. , Udupi R.H.

DOI:         Access: Open Access Read More

Author(s): B. Ranga Nayakulu, Nakka Ravi Kumar, Ch. Kiran Kumar, P. Raja Abhilash

DOI: 10.5958/2231-5713.2016.00012.X         Access: Open Access Read More

Asian Journal of Pharmacy and Technology (AJPTech.) is an international, peer-reviewed journal, devoted to pharmaceutical sciences...... Read more >>>

RNI: Not Available                     
DOI: 10.5958/2231–5713 


Recent Articles




Tags