Preparation of Sustained Release Matrix Dispersion type Transdermal films of Lornoxicam

Ravindra Babu Baggi

doi:10.5958/2231-5713.2018.00012.0

Asian Journal of Pharmacy and Technology

ISSN

2231-5713 (Online)
2231-5705 (Print)

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Preparation of Sustained Release Matrix Dispersion type Transdermal films of Lornoxicam

Author(s): Ravindra Babu Baggi

Email(s): baggi.ravi69@gmail.com

DOI: 10.5958/2231-5713.2018.00012.0

Address: Dr. Ravindra Babu Baggi
Department of Pharmaceutics, Pulla Reddy Institute of Pharmacy, Hyderabad-502 313.
*Corresponding Author

Published In: Volume - 8, Issue - 2, Year - 2018

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ABSTRACT:
Transdermal drug delivery systems of Lornoxicam have been formulated by using solvent casting method. Matrix patches were prepared by using Chitosan and different grades of hydroxyl propyl methyl cellulose (HPMC) as polymers by incorporating glycerol as plasticizer and Tween-80 as permeation enhancer. All the patches were uniform with respect to physicochemical and FTIR evaluation. The invitro permeation studies indicated that matrix patches containing Chitosan: HPMCk100 in the ratio of 1:2 shown better release. Tween-80 was incorporated to enhance the permeation of drug. The formulation containing 30% w/w glycerol has exhibited better enhancement for the permeation of Lornoxicam. Skin irritation study revealed that the free of irritation.

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Cite this article:
Ravindra Babu Baggi. Preparation of Sustained Release Matrix Dispersion type Transdermal films of Lornoxicam. Asian J. Pharm. Tech. 2018; 8 (2):78-82. doi: 10.5958/2231-5713.2018.00012.0

Cite(Electronic):
Ravindra Babu Baggi. Preparation of Sustained Release Matrix Dispersion type Transdermal films of Lornoxicam. Asian J. Pharm. Tech. 2018; 8 (2):78-82. doi: 10.5958/2231-5713.2018.00012.0 Available on: https://ajptonline.com/AbstractView.aspx?PID=2018-8-2-3

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DOI: 10.5958/2231–5713