Author(s):
Shivali1, Priyankul Palia, Sunny Dhiman, Inder Kumar, Pankaj Kumar, Vikrant Dalwal
Email(s):
priyankulpalia23@gmail.com
DOI:
10.52711/2231-5713.2024.00034 
Address:
Shivali1, Priyankul Palia1*, Sunny Dhiman1, Inder Kumar2, Pankaj Kumar1, Vikrant Dalwal1
1School of Pharmacy, Abhilashi University, Chail-Chowk, Mandi, Himachal Pradesh, India.
2Minerva College of Pharmacy, Indora, Distt. Kangra, HP, India.
*Corresponding Author
Published In:
Volume - 14,
Issue - 3,
Year - 2024
ABSTRACT:
Biphenyls are polynuclear aromatic hydrocarbons with a molecular formula (C12 H10) having more than one aromatic nucleus. Biphenyl derivatives substituted with an aromatic or heteroaromatic radical have therapeutic use in pharmaceutical compositions intended for use in humans or cosmetic compositions. The present study included the synthesis of biphenyls derivatives and their antifungal and antimicrobial activities. Four different compounds (SCPD1-SCPD4) were synthesized via different synthesis methods. All the compounds were characterized by different methods like TLC, IR, and NMR. All the peaks and spectra revealed the presence of synthesized compounds. Among all the synthesized compounds, SCPD3 has shown maximum activity against gram-negative E. coli, and SCPD4 has shown maximum activity against C. albicans when compared with standard drug ketoconazole. The series of biphenyl derivatives may be a potent alternative to some other antibacterial and antifungal agents.
Cite this article:
Shivali1, Priyankul Palia, Sunny Dhiman, Inder Kumar, Pankaj Kumar, Vikrant Dalwal. Synthesis, Characterization and Antimicrobial Evaluation of Biphenyl derivatives against C. albicans and E. coli. Asian Journal of Pharmacy and Technology. 2024; 14(3):208-2. doi: 10.52711/2231-5713.2024.00034
Cite(Electronic):
Shivali1, Priyankul Palia, Sunny Dhiman, Inder Kumar, Pankaj Kumar, Vikrant Dalwal. Synthesis, Characterization and Antimicrobial Evaluation of Biphenyl derivatives against C. albicans and E. coli. Asian Journal of Pharmacy and Technology. 2024; 14(3):208-2. doi: 10.52711/2231-5713.2024.00034 Available on: https://ajptonline.com/AbstractView.aspx?PID=2024-14-3-3
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