ABSTRACT:
Bioelectronic medicine is a relatively new area that focuses on developing methods for treating diseases that do not need medications. Bioelectronic medicine treatments are now possible thanks to a small embedded system that produces and delivers frequent digital doses to nerve bundles, resulting in a disease-fighting effect that can last hours or days and is based on mechanisms similar to drug therapies. Although this may sound like science fiction, electronic brain and nerve stimulators are now presence applicable to treat so many of ailments, including epilepsy, Parkinson's disease, and bladder control. Progress in treating such disorders has opened up possibilities for boosting memory, improving eyesight, strengthening a shaky gait, and even improving a golfer's swing. Those self-improvement dreams may be a long way off, but bioelectronic medicine is gaining traction as a new way to treat difficult diseases. What distinguishes bioelectronic medicine is its biological effect on the body, which goes beyond symptom management to treat the underlying condition by using the body's own mechanisms. With promising early results in many trials and further trials ongoing, bioelectronic therapies are likely to be accepted for clinical use within the next few years. To make this advancement possible, forward-thinking scientists, engineers, doctors, and innovators with specialised talents combined old and new discoveries in ways no one had before.
Cite this article:
Vikram B. Madane, Sasmit N. Mali. Bioelectric Medicine: Magicall Tools for Treatment of Many Diseases. Asian Journal of Pharmacy and Technology. 2021; 11(4):304-8. doi: 10.52711/2231-5713.2021.00052
Cite(Electronic):
Vikram B. Madane, Sasmit N. Mali. Bioelectric Medicine: Magicall Tools for Treatment of Many Diseases. Asian Journal of Pharmacy and Technology. 2021; 11(4):304-8. doi: 10.52711/2231-5713.2021.00052 Available on: https://ajptonline.com/AbstractView.aspx?PID=2021-11-4-10
REFERENCES:
1. Chaudhary S Patel A. and., International Journal of Pharmaceutical Science Research, 2020Vol. 11(9): 4229-4237.
2. Giagka V, Serdijn WA. Realizing flexible bioelectronic medicines for accessing the peripheral nerves–technology considerations. Bioelectronic Medicine. 2018 Dec; 4(1): 1-0.
3. Anikeeva P, Birmingham K, Gradinaru V, Grill WM, Pikov V, McLaughlin B, Pasricha P, Weber D, Ludwig K, Famm K. Bioelectronic medicines: a research roadmap. Nature Reviews Drug Discovery. 2014 Jun; 13(6): 399-400.
4. Chiu IM, Lai NY, Mills K. Sensory neuron regulation of gastrointestinal inflammation and bacterial host defence. Journal of Internal Medicine. 2017 Jul; 282(1):5-23.
5. Abidian MR, Fattahi P, Kim G, Yang G. A review of organic and inorganic biomaterials for neural interfaces. Advanced Materials. 2014 Mar; 26(12):1846-85.
6. Axon RN, Brzezinski WA, Egan BM, Zhao Y, Ferdinand KC. Uncontrolled and apparent treatment resistant hypertension in the United States, 1988 to 2008. Circulation. 2011 Aug 30;124(9): 1046-58.
7. Bisognano JD, Bakris G, De Leeuw PW, Kroon AA, Nadim MK, Sanchez L, Schafer J, Sica DA. Baroreflex activation therapy lowers blood pressure in patients with resistant hypertension: results from the double-blind, randomized, placebo-controlled rheos pivotal trial. Journal of the American College of Cardiology. 2011 Aug 9; 58(7): 765-73.
8. Abe SI, Cho KH, Hieda K, Jang HS, Kim JH, Murakami G, Matsubara A. Composite nerve fibers in the hypogastric and pelvic splanchnic nerves: an immunohistochemical study using elderly cadavers. Anatomy & Cell Biology. 2015 Jun; 48(2): 114.
9. Pooja Sangelkar, Pranali Joshi, Sairaj Gawade, Shraddha Kanekar, Siddhesh Gosavi, Vidur Bhogate. Comparative Study on Treatment of Rheumatoid Arthritis. Asian J. Pharm. Tech. 2021; 11(1): 5-12.
10. Chirag K Patel, B Panigrahi, R Badmanaban, CN Patel. Biochemical Origins of Alzheimer’s Disease with Treatment Techniques. Research J. Pharmacology and Pharmacodynamics. 2010; 2(1): 33-38.
11. Schouenborg J. Biocompatible multichannel electrodes for long-term neurophysiological studies and clinical therapy—novel concepts and design. Progress in Brain Research. 2011 Jan 1;194: 61-70.
12. Binder LM. Persisting symptoms after mild head injury: A review of the postconcussive syndrome. Journal of Clinical and Experimental Neuropsychology. 1986 Aug 1; 8(4): 323-46.
13. Deependra Singh, Mukesh K Nag, Satish Patel, Madhulika Pradhan, Shikha Shrivastava, SJ Daharwal, Manju R Singh. Treatment Strategies in Burn Wounds: An Overview. Research J. Pharmacology and Pharmacodynamics. 2013; 5(6): 341-352.
14. Adlan AM, Lip GY, Paton JF, Kitas GD, Fisher JP. Autonomic function and rheumatoid arthritis—A systematic review. In Seminars in Arthritis and Rheumatism 2014 Dec 1 (Vol. 44, No. 3, pp. 283-304). WB Saunders.
15. McFarland DJ, Sarnacki WA, Wolpaw JR. Electroencephalographic (EEG) control of three-dimensional movement. Journal of Neural Engineering. 2010 May 11; 7(3): 036007.
16. Koopman FA, Tang MW, Vermeij J, De Hair MJ, Choi IY, Vervoordeldonk MJ, Gerlag DM, Karemaker JM, Tak PP. Autonomic dysfunction precedes development of rheumatoid arthritis: a prospective cohort study. EBioMedicine. 2016 Apr 1;6: 231-7.
17. Siddhesh Gosavi, Pranali Joshi, Vidur Bhogate, Sairaj Gawade, Pooja Sangelkar, Shraddha Kanekar. Comparative Study on Treatment of Rheumatoid Arthritis. Asian J. Pharm. Tech. 2021; 11(1): 5-12.
18. O’Doherty JE, Lebedev MA, Ifft PJ, Zhuang KZ, Shokur S, Bleuler H, Nicolelis MA. Active tactile exploration using a brain– machine–brain interface. Nature. 2011 Nov;479(7372): 228-31.
19. Venkatraman S, Carmena JM. Active sensing of target location encoded by cortical microstimulation. IEEE Transactions on Neural Systems and Rehabilitation Engineering. 2011 Mar 3; 19(3): 317-24.
20. Chirag K Patel, B Panigrahi, R Badmanaban, CN Patel. Biochemical Origins of Alzheimer’s Disease with Treatment Techniques. Research J. Pharmacology and Pharmacodynamics. 2010; 2(1): 33-38.
21. Koopman FA, Stoof SP, Straub RH, Van Maanen MA, Vervoordeldonk MJ, Tak PP. Restoring the balance of the autonomic nervous system as an innovative approach to the treatment of rheumatoid arthritis. Molecular Medicine. 2011 Sep;17(9): 937-48.
22. Tang R, Pei W, Chen S, Zhao H, Chen Y, Han Y, Wang C, Chen H. Fabrication of strongly adherent platinum black coatings on microelectrodes array. Science China Information Sciences. 2014 Apr; 57(4): 1-0.
23. Marinov V, Swenson O, Miller R, Sarwar F, Atanasov Y, Semler M, Datta S. Laser-enabled advanced packaging of ultrathin bare dice in flexible substrates. IEEE Transactions on Components, Packaging and Manufacturing Technology. 2011 Dec 29; 2(4): 569-77.
24. Manu Kohli, Gaurav Kohli. Understanding of Naturopathy. Int. J. Nur. Edu. and Research 2(2): April- June 2014; Page 135-139.
25. Jain LC, Halici U, Hayashi I, Lee SB, Tsutsui S, editors. Intelligent biometric techniques in fingerprint and face recognition. CRC press; 1999 Jun 29.
26. Vaidya VP, Ingole SA, Gautam LK, Gadbail RN, Gulhane VS. Bionic Eye, Restores Sight to the Blind. International Journal of Computer Science & Communication. 2010 Dec; 1(2): 251-3
27. Jain AK, Hong L, Pankanti S, Bolle R. An identity-authentication system using fingerprints. Proceedings of the IEEE. 1997 Sep; 85(9): 365-88.
28. Sahoo CK, Rao SR, Sudhakar M, Ramana DV, Satyanarayana K. Formulation and optimization of porous osmotic pump based controlled release system of Ritonavir for the treatment of HIV infection. Magnesium. 2018 Mar 22; 40(60): 80.
29. Deependra Singh, Mukesh K Nag, Satish Patel, Madhulika Pradhan, Shikha Shrivastava, SJ Daharwal, Manju R Singh. Treatment Strategies in Burn Wounds: An Overview. Research J. Pharmacology and Pharmacodynamics. 2013; 5(6): 341-352.
30. Roshni Solanki, Dhaval Madat, Khushbu Chauhan, Lalkrushn Parmar. New Approaches in the Treatment of Inflammatory Bowel Disease. Research J. Pharmacology and Pharmacodynamics. 2010; 2(3): 228-232.
31. K. Kameswararao, Ch. Sujani, N.V. N Koteswararao, A. Rajarao, P.N.S. Satyanarayanamma. A Brief Review on Acne Vulgaris. Res. J. Pharmacology and Pharmacodynamics.2019; 11(3):109-119.