Author(s): B. Hemalatha, T. Pavani Priya, K. Manasa, Ch. Greeshmika, P. Kavya, Shaik Sayeeda Sarah, K. Padmalatha

Email(s): balahemalatha25@gmail.com

DOI: 10.52711/2231-5713.2022.00038   

Address: B. Hemalatha1*, T. Pavani Priya1, K. Manasa1, Ch. Greeshmika1, P. Kavya1, Shaik Sayeeda Sarah1, K. Padmalatha2
1Department of Pharmaceutics, Vijaya Institute of Pharmaceutical Sciences for Women, Vijayawada.
2Department of Pharmacology, Vijaya Institute of Pharmaceutical Sciences for Women, Vijayawada.
*Corresponding Author

Published In:   Volume - 12,      Issue - 3,     Year - 2022


ABSTRACT:
Emulgel is one of the promising topical drug delivery system for the delivery of hydrophobic drugs which overcome a variety of disadvantages of ointments and creams like greasiness as well as phase inversion. The aim of present work was to develop and evaluate Oxiconazole emulgel. Oxiconazole emulgel was prepared by using polymers like Carbopol 934 and HPMC K4M at different concentrations. Oxiconazole is a broad spectrum anti - fungal agent used in treat of various skin infections such as athlete’s foot, jock itch and ring worm. The prepared emulgels were evaluated in terms of physical appearance, measurement of pH, viscosity, spreadability, drug content and in vitro diffusion studies and skin irritation study. Formulation F1 containing carbapol 934 is considered as optimized formulation because it showed highest drug release i.e., 58.57% in 8 hrs.


Cite this article:
B. Hemalatha, T. Pavani Priya, K. Manasa, Ch. Greeshmika, P. Kavya, Shaik Sayeeda Sarah, K. Padmalatha. Optimization of Oxiconazole Topical Emulgel Formulation for the Treatment of Skin Infections. Asian Journal of Pharmacy and Technology. 2022; 12(3):232-6. doi: 10.52711/2231-5713.2022.00038

Cite(Electronic):
B. Hemalatha, T. Pavani Priya, K. Manasa, Ch. Greeshmika, P. Kavya, Shaik Sayeeda Sarah, K. Padmalatha. Optimization of Oxiconazole Topical Emulgel Formulation for the Treatment of Skin Infections. Asian Journal of Pharmacy and Technology. 2022; 12(3):232-6. doi: 10.52711/2231-5713.2022.00038   Available on: https://ajptonline.com/AbstractView.aspx?PID=2022-12-3-7


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