Author(s): Rina G. Maskare, Shital D. Thakre, Om D. Patle, Shirali S. Vishwakarma, Dhyanesh N. Dahake, Rima J. Jagnit, Rohit S. Rahangdale

Email(s): rinamaskare@yahoo.co.in

DOI: 10.52711/2231-5713.2023.00004   

Address: Rina G. Maskare, Shital D. Thakre, Om D. Patle, Shirali S. Vishwakarma, Dhyanesh N. Dahake, Rima J. Jagnit, Rohit S. Rahangdale
Manoharbhai Patel Institute of B-Pharmacy, Kudwa, Gondia. 441614.
*Corresponding Author

Published In:   Volume - 13,      Issue - 1,     Year - 2023


ABSTRACT:
Mouth ulcer also known as cankers ulcer are normally small painful abscess that can develop in your mouth or the base of your gum due to these we feel uncomfortable in eating, drinking and talking. Women’s, adolescent and people with a family history of mouth ulcers are higher risk for developing mouth ulcer. There is no major drug therapy required for treatment of mouth ulcer, usually people prefer home remedies. But it is not convenient to take , dose variation may occur because there is no definite quantity given, and also it is unpleasant sometimes irritable thus accordingly we formulate candy like formulation that is lozenges which composed of herbal ingredient like, guava leaves , pigeon pea leave, Tulsi, mint, turmeric, liquorice, clove binded with dextrose , which is convenient for patient The prepared lozengesare evaluated for stability parameter, according to ICH Guideline, the improved formulative lozenges where evaluated for physical characters and results comes under pharmacopeial limit. In-vitro dissolution study show’s 90 % drug release within 30 minutes, the stability studies shows that formulation is stable for last 3 months. Here antimicrobial activity of lozenges is also studied and it shows the positive result for topical application. From recent work it was assured that the herbal lozenges can be considered as a reliable delivery system for the treatment of mouth ulcer.


Cite this article:
Rina G. Maskare, Shital D. Thakre, Om D. Patle, Shirali S. Vishwakarma, Dhyanesh N. Dahake, Rima J. Jagnit, Rohit S. Rahangdale. Novel Formulation for Treatment of Mouth Ulcer. Asian Journal of Pharmacy and Technology. 2023; 13(1):19-4. doi: 10.52711/2231-5713.2023.00004

Cite(Electronic):
Rina G. Maskare, Shital D. Thakre, Om D. Patle, Shirali S. Vishwakarma, Dhyanesh N. Dahake, Rima J. Jagnit, Rohit S. Rahangdale. Novel Formulation for Treatment of Mouth Ulcer. Asian Journal of Pharmacy and Technology. 2023; 13(1):19-4. doi: 10.52711/2231-5713.2023.00004   Available on: https://ajptonline.com/AbstractView.aspx?PID=2023-13-1-4


REFERENCES:
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2.    Mishra, K.K., Tasneem, K., Jain, V. and Mahajan, S.C., 2017. Formulation and evaluation of herbal lozenges. Journal of Drug Delivery and Therapeutics, 7(7), pp.87-90.
3.    Bhandarkar, A., Alexander, A., Bhatt, A., Sahu, P., Agrawal, P., Banjare, T., Gupta, S., Sahu, H., Diwedi, S.D., Sahu, S.K. and Yadav, P., 2018. Formulation and Evaluation of Ascorbic acid Lozenges for the treatment of Oral Ulcer. Research Journal of Pharmacy and Technology, 11(4), pp.1307-1312.
4.    Anderson, A.M., Mitchell, M.S. and Mohan, R.S., 2000. Isolation of curcumin from turmeric. Journal of chemical education, 77(3), p.359.
5.    Overly, K.R., 2019. Microwave-Assisted Isolation of Eugenol from Cloves. Journal of Chemical Education, 96(11), pp.2665-2667.
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10.    Thombre, K.P., Sharma, D. and Lanjewar, A.M., 2018. Formulation and evaluation pharmaceutical aqueous gel of powdered Cordia dichotoma leaves with guava leaves. American Journal of Pharmatech Research, 8(2), pp.268-277.
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