Author(s): Nikita D. Gidde, Indrayani D. Raut

Email(s): nikitagidde19@gmail.com

DOI: 10.52711/2231-5713.2023.00020   

Address: Nikita D. Gidde1*, Indrayani D. Raut2
1Department of Pharmaceutics, Adarsh College of Pharmacy, Vita. (MS) India 415311.
2Department of Pharmaceutics, Rajarambapu College of Pharmacy, Kasegaon (MS) India 415404.
*Corresponding Author

Published In:   Volume - 13,      Issue - 2,     Year - 2023


ABSTRACT:
Microspheres are mainly free flowing powders consisting of proteins or synthetic polymers. Proteins or synthetic polymers are biodegradable in nature. Microspheres having a particle size less than 200 micrometer. Microspheres are novel drug delivery system which has several benefits over conventional multi dose therapy. There are various approaches in delivering a therapeutic agent to the specific targeted site in a sustained controlled release fashion. Microsphere is act as carriers for drugs. Microspheres received much attention for prolonged release as well as for targeting of anticancer drug to the tumour. In this drug delivery, drug dispersed throughout the particle i.e., the internal structure is a drug matrix and polymeric excipients. It is the reliable means delivery of the drug to the target site with specificity, if modified, and to maintain the desired concentration at the site of interest without untoward effects. In future microspheres will find an appropriate place in novel delivery by combining various new strategies, particularly in diseased cell sorting, diagnostic, gene and genetic materials, safe, targeted and effective in vivo delivery. The current aim of this review is to study the various aspects of microspheres drug delivery system including advantages, disadvantages, types of microspheres, methods of preparations, Evaluations and Applications of microspheres.


Cite this article:
Nikita D. Gidde, Indrayani D. Raut. Microsphere as Drug Delivery System: An Overview. Asian Journal of Pharmacy and Technology. 2023; 13(2):105-0. doi: 10.52711/2231-5713.2023.00020

Cite(Electronic):
Nikita D. Gidde, Indrayani D. Raut. Microsphere as Drug Delivery System: An Overview. Asian Journal of Pharmacy and Technology. 2023; 13(2):105-0. doi: 10.52711/2231-5713.2023.00020   Available on: https://ajptonline.com/AbstractView.aspx?PID=2023-13-2-6


REFERENCES:
1.    Vikrant k. Nikam1, V. R. Gudsoorkar, S. N. Hiremath1, R.T. Dolas and V. A.  Kashid et al. Microspheres - A Novel Drug Delivery System: An Overview, 2012; 1 (1) : 114.
2.    R. K. Khar, S. P. Vyas, et al., Targeted and controlled drug delivery- novel carrier systems., 1st edition, CBS Publications and Distributors, New Delhi, 2002; 417-418.
3.    N. R. Kadam and V. Suvarna Microspheres: a brief review, Asian Journal of Biomedical and Pharmaceutical Sciences, 2015; 5(47):14 -15.
4.    M. Alagu Sundaram, Madhu Sudanachetty.C, Uma Shankari.K, Ttuluri Venkatabadarinath, C. Lavanya, and S. Ramkanth, et al. Microspheres as a novel drug delivery sytem - A Review, International Journal of Chemtech Res.2009; 1(3):527-529.
5.    C. Singh, S. Purohit, M. Singh, B. Pandey, et al. Design and evaluation of microspheres: a review, JDDR. 2013; 2(2):18-27.
6.    H. Parmar, S. Bakliwal, N. Gujarathi, B. Rane, S. Pawar, et al. Different Methods of Formulation and Evaluation of Mucoadhesive Microsphere, International Journal of Applied Biology and Pharmaceutical Technology, 2010; 1(3):1157-67.
7.    K. Sahil, M. Akanksha, S. Premjeet, A. Bilandi, B. Kapoor, et al. Microsphere: a Review. Int. J. Res. Pharm. Chem., 2011; 1:118498.
8.    B. Pavan Kumar, I. S. Chandiran, B. Bhavya,  M. Sindhuri, et al .Microparticulate drug delivery system: a review, Indian Journal of Pharmaceutical Science & Research, 2011; 1(1):19-37.
9.    D. S Mali, S. G. Talele, R. Mogal, G. Chaudhari, et al. Review on nasal microspheres, am. J. Pharm Techres, 2014; 4(1):97-111.
10.    T. Virmani and J. Gupta Et al Pharmaceutical Application of Microspheres: An Approach for The Treatment of Various Diseases, International Journal Of
Pharmaceutical Sciences and Research, Projected Impact Factor (2019); 1:230.
11.    Gyanesh sahu, Harish Sharma, Chanchal Deep Kaur. A novel approach of magnetic modulated microspheres. Asian J. Pharm. Res. 3(4): oct. - dec.2013;  page 220-224.
12.    Rutuja S. Shah, Rutuja R. Shah, Manoj M. Nitalikar, Chandrakant S. Magdum. Microspheres by spray drying: an approach to enhance solubility of bicalutamide. Asian J. Pharm. Res. 2017;  7(3): 183-188.
13.    Kaustubh V. Gavali, Manohar D. Kengar, Kiran V. Chavan, Vaishnavi P. Anekar, Naziya I. Khan. A review on microsphere and it’s application. Asian J. Pharm. Res. 2019;  9(2): 123-129.
14.    Vishal Mahanur, Yash Sureka, Virendra Atole. A review on magnetic microspheres- a novel drug delivery system. Asian Journal of Research in Pharmaceutical Sciences. 2022; 12(1):57-1.
15.    Dhadde Gurunath S., Mali Hanmant S., Raut Indrayani D., Nitalikar Manoj M., Bhutkar Mangesh A. A review on microspheres: types, method of preparation, characterization and application. Asian Journal of Pharmacy and Technology. 2021;  11(2):149-5.
16.    Wajid Ahmad, Jaza Quazi, Reshma Khan, Nadeem Ahmad, Nawed Ansari. A comprehensive review on microspheres. Asian Journal of Pharmacy and Technology. 2022; 12(2):136-0.
17.    Rajesh Mujoriya. A review on study of microsphere. Research j. Pharma. Dosage Forms and Tech. 2012; 4(2): 80-85
18.    Rutuja K. More, Diksha S. Sonawane, Moreshwar P. Patil, Sanjay J. Kshirsagar. Rutuja K. More, Diksha S. Sonawane, Moreshwar P. Patil, Sanjay J. Kshirsagar. Res. J. Pharma. Dosage Forms and Tech. 2018; 10(3): 193-199.
19.    A.G. Chintale, V.S. Kadam, K.S. Maske, D.B. Raut, S.V. Kale, S.D. Rai. Recent advances in microsphere drug delivery system: a review. Research J. Pharm. and Tech. 6(3): March 2013;  Page 307-312.
20.    Ashwin Kumar Saxena, Aditya Sharma, Navneet Verma. Microspheres as Therapeutically effective Multiparticulate Drug Delivery System: A Systemic Review. Research Journal of Pharmacy and Technology. 2021; 14(6):3461-0.
21.    Deepak S. Kshirsagar, R. B. Saudagar. Microsphere: A Review. Research J. Topical and Cosmetic Sci. 2016; 7(1): 27-37.

Recomonded Articles:

Author(s): Juveriya Fatima, Saniya Khan, Nuha Rasheed, Abdul Saleem Mohammad

DOI: 10.5958/2231-5713.2017.00009.5         Access: Open Access Read More

Author(s): Manohar D. Kengar, Rohit S. Howal, Dattatray B. Aundhakar, Amit V. Nikam, Priyajit S. Hasabe

DOI: 10.5958/2231-5713.2019.00010.2         Access: Open Access Read More

Author(s): Anuradha A Sawant, S.K. Mohite.

DOI: 10.5958/2231-5713.2015.00014.8         Access: Open Access Read More

Author(s): Abhijit Ray

DOI:         Access: Open Access Read More

Author(s): Wajid Ahmad, Jaza Quazi, Reshma Khan, Nadeem Ahmad, Nawed Ansari

DOI: 10.52711/2231-5713.2022.00023         Access: Open Access Read More

Author(s): Kanchan R. Pagar, Sarika V. Khandbahale

DOI: 10.5958/2231-5713.2019.00023.0         Access: Open Access Read More

Author(s): Ruchika Sharma, M. S. Ashawat, C. P. S Verma, Neha Kumari

DOI: 10.5958/2231-5713.2020.00039.2         Access: Open Access Read More

Author(s): Nizamudeen.T, Ramanjaneyulu. J, Veeresh Babu. D, Narayana Swamy V.B

DOI: 10.5958/2231-5713.2015.00017.3         Access: Open Access Read More

Author(s): Chinmaya Keshari Sahoo, K. Satyanarayana, D. Venkata Ramana, Kanhu Charan Panda

DOI: 10.5958/2231-5713.2017.00034.4         Access: Open Access Read More

Author(s): Rutuja Saurabh Shah

DOI: 10.52711/2231-5713.2021.00035         Access: Open Access Read More

Author(s): Durgesh Gautam, Preetam Palkar, Kiran Maule, Shilpa Singh, Gopika Sawant, Chinmay Kuvalekar, Tushar Rukari, Vijay A. Jagtap

DOI: 10.5958/2231-5713.2020.00028.8         Access: Open Access Read More

Author(s): Yogita. Chowdhary

DOI: 10.5958/2231-5713.2018.00002.8         Access: Open Access Read More

Author(s): Phatak Atul A., Chaudhari Praveen D.

DOI:         Access: Open Access Read More

Author(s): A. Elumalai, Nikhitha Mathangi, Adarsh Didala, Raju Kasarla, Yetcharla Venkatesh

DOI:         Access: Open Access Read More

Author(s): Indrajeet V. Mane, Abhishek S. Pujari, Nitin A. Gaikwad, Rajeshwar V. Chavan, Ganesh B. Vambhurkar

DOI: 10.5958/2231-5713.2018.00030.2         Access: Open Access Read More

Author(s): Dhadde Gurunath S., Mali Hanmant S., Raut Indrayani D., Nitalikar Manoj M., Bhutkar Mangesh A.

DOI: 10.52711/2231-5713.2021.00025         Access: Open Access Read More

Author(s): Abdul Saleem Mohammad, Swetha Devidi, Nikhat Fatima, Humera Badar, Syeda Saba Sulthana, Mohammad Akthar Sulthana, Nuha Rasheed

DOI:         Access: Open Access Read More

Asian Journal of Pharmacy and Technology (AJPTech.) is an international, peer-reviewed journal, devoted to pharmaceutical sciences...... Read more >>>

RNI: Not Available                     
DOI: 10.5958/2231–5713 


Recent Articles




Tags