Author(s): Madhurima Thakur, Sunny Dhiman

Email(s): sdsdhiman1@gmail.com

DOI: 10.52711/2231-5713.2023.00046   

Address: Madhurima Thakur1, Sunny Dhiman2*
1School of Pharmacy, Abhilashi University, Mandi, HP, India.
2Chandigarh College of Pharmacy CGC Landran, Mohali, Punjab, India.
*Corresponding Author

Published In:   Volume - 13,      Issue - 4,     Year - 2023


ABSTRACT:
Indian Systems of Medicine have their roots in ayurveda. The potential of naturally occurring bioactive components is of tremendous interest to researchers. Different plant extracts have remedial properties.North India, Japan, China, Korea and Nepal are among the countries where Artemisia princeps can be found.Apigenin, diosmetin, eriiodicytol, eupafolin, kaempferol, vitex, jaceosidine, and quercetins have all been discovered in plant extracts of Artemisia princeps.It is used to treat fever, apoptosis, pain, ulcers, inflammation, and other conditions as well as Diarrhoea and Asthma.Recent in-vivo and in-vitro research have shown that it has anti-inflammatory and analgesic properties. The objectives of proposed research work are to formulate, evaluate and optimize the Emulgel loaded with optimised extract of Artemisia princepsand assess its In-Vitro Anti-Inflammatory Activity. Collected leaves of Artemisia princeps was extracted using hydro-alcoholic solvent. On the basis of their Phytochemical evaluation, the extract was optimized. Additional 6 batches of Emulgel were created utilizing a chosen extract. The prepared Emulgel was assessed for pH, spreadability, viscosity, consistency, appearance, colour, infrared spectral assignment, and appearance. Using the HRBC Membrane stabilisation assay, extract and formulation were tested for in vitro anti-inflammatory efficacy. The suggested study project's findings support the potential for future topical application of the newly developed Emulgel, which contains Artemisia princeps leaf extract, to reduce inflammation.


Cite this article:
Madhurima Thakur, Sunny Dhiman. Formulation and Evaluation of Emulgel loaded with leaf extract of Artemisia princeps for its Anti-Inflammatory potential. Asian Journal of Pharmacy and Technology. 2023; 13(4):257-2. doi: 10.52711/2231-5713.2023.00046

Cite(Electronic):
Madhurima Thakur, Sunny Dhiman. Formulation and Evaluation of Emulgel loaded with leaf extract of Artemisia princeps for its Anti-Inflammatory potential. Asian Journal of Pharmacy and Technology. 2023; 13(4):257-2. doi: 10.52711/2231-5713.2023.00046   Available on: https://ajptonline.com/AbstractView.aspx?PID=2023-13-4-4


REFERENCES:
1.    Wayal S, Gurav S. Pharmacognostic and phytochemical investigation of potentially important plants of Western Ghats, India. Int J Pharm Sci Res. 2019; 10(6):3101-8.
2.    Giri S, Dey G, Sahu R, Paul P, Nandi G, Dua T. Traditional Uses, Phytochemistry and Pharmacological Activities of Woodfordia fruticosa (L) Kurz: A Comprehensive Review. Indian Journal of Pharmaceutical Sciences. 2023; 85(1).
3.    Sudipta K, Lokesh P, Rashmi W, Vijay R, Ssn K. Phytochemical screening and in vitro antimicrobial activity of Bougainvillea spectabilis flower extracts. International Journal of Phytomedicine. 2012; 4(3):375.
4.    Saonere JA, Channawar M, Mohale D, Chandewar AV. In-vitro Evaluation of Antioxidant and Photoprotective Activity of Sida cardifolia and Abutilon indicum. Asian Journal of Pharmacy and Technology. 2023; 13(2).
5.    Pal SK, Shukla Y. Herbal medicine: current status and the future. Asian Pacific Journal of Cancer Prevention. 2003; 4(4):281-8.
6.    HoChang S, Jung EJ, Park YH, Lim DG, Ko NY, Choi WS, et al. Anti-inflammatory effects of Artemisia princeps in antigen-stimulated T cells and regulatory T cells. Journal of Pharmacy and Pharmacology. 2009; 61(8):1043-50.
7.    Singh A. A Review of various aspects of the Ethnopharmacological, Phytochemical, Pharmacognostical, and Clinical significance of selected Medicinal plants. Asian Journal of Pharmacy and Technology. 2022; 12(4):349-60.
8.    Chauhan V, Nautiyal A. A review: Health benefits of herbal plants in nutraceuticals. Asian Journal of Pharmacy and Technology. 2022; 12(3):277-81.
9.    CHEN J, CHEN G. Advances in Research on Chemical Components and Pharmacological Activities of Artemisia Princeps. Journal of Jishou University (Natural Sciences Edition). 2020; 41(2):46.
10.    Yadav SK, Mishra MK, Tiwari A, Shukla A. Emulgel: a new approach for enhanced topical drug delivery. Int J Curr Pharm Res. 2016; 9(1):15-9.
11.    Derouiche S, Cheradid T, Guessoum M. Heavy metals, oxidative stress and inflammation in pathophysiology of chronic kidney disease-a review. Asian Journal of Pharmacy and Technology. 2020; 10(3):202-6.
12.    Goli V, Bhaskar KV, Macharla SP, Bhaskar J, Devi PS, Ramchander T. Effects of anti-Inflammatory activity of Mimosa pudica. Asian Journal of Pharmaceutical Research. 2011; 1(3):69-71.
13.    Manvar MN, Desai T. In-vitro anti-inflammatory and anti-arthritic activities of fruits of Vernonia anthelmintica Willd.(Asteraceae). Asian Journal of Pharmaceutical Research. 2014; 4(4):186-8.
14.    Ahmad A, Niranjan AK. Formulation And Evaluation Of Herbal Oral Emulgel Containing Psidium Guajava Linn. Leaves Extract (A Preventive Oral Care Preparation). Asian J Pharm Clin Res. 2021; 14(12):93-5.
15.    Shah RS. Formulation and evaluation of Turmeric emulgel. Asian Journal of Pharmacy and Technology. 2021; 11(3):213-9.
16.    Yadav A, Mishra DK, Paliwal P, Farooqui N, Gawshinde A. Formulation and evaluation of polyherbal antiaging cream. Asian Journal of Pharmacy and Technology. 2021; 11(4):284-8.
17.    Redkar MR, Hasabe PS, Jadhav ST, Mane PS, Kare DJ. Review on optimization base emulgel formulation. Asian Journal of Pharmacy and Technology. 2019; 9(3):228-37.
18.    Latha A, Kumar J, Sojana N, Mounika N, Priyanka G, Venkatesh A. Design and Optimization of Clotrimazole Emulgel by using various Polymers. Asian Journal of Pharmacy and Technology. 2021; 11(1):41-7.
19.    Shaikh HS, Shaikh SS. Babchi (Psoralea corylifolia): From a variety of traditional medicinal application to its novel roles in various diseases: A review. Asian Journal of Pharmacy and Technology. 2021; 11(3):238-44.
20.    Rajan S, Nair SS, Sreena K, Sabari S. Preparation and evaluation of ketoprofen film forming gel. European J Pharm Med Res. 2022; 9(9):212-19.
21.    Sawant AA, Mohite S. Formulation and evaluation of itraconazole emulgel for topical drug delivery. Asian Journal of Pharmacy and Technology. 2015; 5(2):91-6.
22.    Wood JH, Catacalos G, Lieberman S. Adaptation of commercial viscometers for special applications in pharmaceutical rheology I: the brookfield viscometer. Journal of Pharmaceutical Sciences. 1963; 52(3):296-8.
23.    Khullar R, Kumar D, Seth N, Saini S. Formulation and evaluation of mefenamic acid emulgel for topical delivery. Saudi Pharmaceutical Journal. 2012; 20(1):63-7.
24.    Gawshinde A, Kamalpuria N, Farooqui N, Choursiya S. Formulation, optimitziation and evaluation of polyherbal anti-dandruff shampoo. Asian Journal of Pharmacy and Technology. 2021; 11(3):220-4.
25.    Muragi A, Samant S, Patil M. Formulation and Evaluation of Herbal Emulgel Loaded with Extract of Cedrus Deodara for its In-vitro Anti-Inflammatory Activity. International Journal of Ayurvedic Medicine. 2022; 13(3):749-53.
26.    Siju P, Ghetia R, Vadher B, Manvar MN. In-Vitro Anti-inflammatory Activity of Fractions of Ailanthus excelsa Roxb. by HRBC Membrane Stabilization. Asian Journal of Pharmacy and Technology. 2015; 5(1):29-31.


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