Author(s): Merlin. N. J, Alfiya. A. R, Shaiju S Dharan

Email(s): merlinbinu76@yahoo.co.in

DOI: 10.5958/2231-5713.2018.00029.6   

Address: Merlin. N. J*, Alfiya. A. R, Shaiju S Dharan
Department of Pharmacology Ezhuthachan College of Pharmaceutical Sciences Marayamuttom Trivandrum
*Corresponding Author

Published In:   Volume - 8,      Issue - 3,     Year - 2018


ABSTRACT:
Toxicokinetics (TK) is ‘the generation of pharmacokinetic data, either as an integral component in the conduct of non-clinical toxicity studies or in specially designed supportive studies, to assess systemic exposure. Physiologically based toxicokinetic [(PBTK), or alternatively referred to as physiologically based pharmacokinetic (PBPK)] models are quantitative descriptions of absorption, distribution, metabolism, and excretion of chemicals. Toxicokinetics, toxicodynamics and toxicogenomics (TK/TD/TG) methods are the potential tools in human health risk assessment.


Cite this article:
Merlin. N. J, Alfiya. A. R, Shaiju S Dharan. Toxicokinetics-A Review. Asian J. Pharm. Tech. 2018; 8 (3):182-185. doi: 10.5958/2231-5713.2018.00029.6


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DOI: 10.5958/2231–5713 


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