ABSTRACT:
Isoniazid is an organic compound. It is a first line drug used in prevention and treatment of tuberculosis also Isoniazid has an anti-depressant effect. Isonicotin hydrazine is also known as isoniazid. A process was developed for the preparation of isoniazid from citric acid via citrazinic acid 2, 6-dichloroisonicotinic acid, isonicotinic acid and ethyl isonicotinate. Yields and procedures in all steps were improved (1).
Cite this article:
Rutuja T Jadhav, Yashvardhan P Bhosale. Synthesis of Isoniazid from Citric Acid. Asian J. Pharm. Tech. 2021; 11(1):1-4. doi: 10.5958/2231-5713.2021.00001.5
Cite(Electronic):
Rutuja T Jadhav, Yashvardhan P Bhosale. Synthesis of Isoniazid from Citric Acid. Asian J. Pharm. Tech. 2021; 11(1):1-4. doi: 10.5958/2231-5713.2021.00001.5 Available on: https://ajptonline.com/AbstractView.aspx?PID=2021-11-1-1
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