Author(s): Vishvajit M. Khade, Sourabh S. Hegaje, Mayuresh R. Redkar, Chetan G. Dhande

Email(s): Email ID Not Available

DOI: 10.5958/2231-5713.2021.00006.4   

Address: Mr. Vishvajit M. Khade1, Mr. Sourabh S. Hegaje1, Mr. Mayuresh R. Redkar2, Mr. Chetan G. Dhande3
1Tatyasaheb Kore College of Pharmacy, Warananagar, Maharashtra, India, 416113.
2Yashwantrao Bhonsale College of Pharmacy Sawantwadi, Maharashtra, India, 416510.
3Shree Santkrupa College of Pharmacy, Ghogaon, Maharashtra, India, 415111.
*Corresponding Author

Published In:   Volume - 11,      Issue - 1,     Year - 2021


ABSTRACT:
The objective of present investigation was to prepare and standardize the churna from the plant materials i.e. Ginger, Garlic, Clove, Neem for anthelmintic activity. The Churna was prepared by taking plant materials, grinding it and was sieved from 80mesh size. The prepared fine powder was then used for testing and standardization. The physicochemical, phytochemical, flow property, TLC was determined. The in-vitro study was carried out on the earthworms for the effect of prepared churna to show the anthelmintic activity. Also the stability study was carried out. The raw material was prepared and authenticated. The churna was prepared by mixing all the ingredients in the fine form. The aqueous and methanol extract of prepared churna showed anthelmintic activity in dose – at 10, 20, and 40 mg/ml concentration for worms. It can be concluded that the active constituents responsible for anthelmintic activity present in the aqueous and methanol extract of prepared churna. The prepared churna is stable, safe, and effective against the helminths and can we used as an anthelmintic.


Cite this article:
Vishvajit M. Khade, Sourabh S. Hegaje, Mayuresh R. Redkar, Chetan G. Dhande. Formulating, Pharmacognostic and Physicochemical Insights of Polyherbal Vermifuge Formulation. Asian J. Pharm. Tech. 2021; 11(1):36-40. doi: 10.5958/2231-5713.2021.00006.4

Cite(Electronic):
Vishvajit M. Khade, Sourabh S. Hegaje, Mayuresh R. Redkar, Chetan G. Dhande. Formulating, Pharmacognostic and Physicochemical Insights of Polyherbal Vermifuge Formulation. Asian J. Pharm. Tech. 2021; 11(1):36-40. doi: 10.5958/2231-5713.2021.00006.4   Available on: https://ajptonline.com/AbstractView.aspx?PID=2021-11-1-6


REFERENCES:
1.    Bahuguna Y., Zaidi S., Kumar N., Rawat K. Standardization of Polyherbal Marketed Formulation Triphala Churna. RRJPP. 2014; 2(3): 28-35.
2.    The Ayurvedic Pharmacopoeia of India Part - II (Formulations) Volume II First Edition‖ Government of India ministry of health and family welfare department of Ayurveda, Yoga and Naturopathy, Unani, Siddha and Homoeopathy, New Delhi 2008, 111-112.
3.    Anonymous- The Ayurvedic Formulary of India‖, Part-II, Govt. of India, Ministery of health and family welfare, Dept. of Indian System of Medicine and Homeopathy, New Delhi.
4.    Anonymous- Quality Standards of Indian Medicinal Plants‖, Published by Indian Council of Medicinal Research, New Delhi, 2003; Vol.1: 89, 198-205.
5.    Khandelwal, K.R, Practical Pharmacognosy, 12th Edition, Nirali Prakashan, Pune, 2004.
6.    Chaturvedi M., et al. Formulation and Evaluation of Polyherbal Anthelmintic Preparation. Ethnobotanical Leaflets. 2009;13: 329-31.
7.    Dwivedi S, et al. Anthelmintic activity of alcoholic and aqueous extract of fruits of Terminalia chebula Retz. Ethanobotanical Leaflets. 2008; 12: 741-43.
8.    Ajaiyeoba EO, Onocha PA, Olarenwaju OT. In vitro anthelmintic properties of Buchholzia coriaceae and Gynandropsis gynandra extract. Pharm Biol. 2001; 39: 217- 20.

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