Author(s):
P. Geetha, M. Varaprasannarao, D. Subalakshmi, R. V. Bibi Bergin
Email(s):
lgeethapharma@gmail.com
DOI:
10.52711/2231-5713.2022.00021 
Address:
P. Geetha, M. Varaprasannarao, D. Subalakshmi, R. V. Bibi Bergin
Department of Pharmacy Practice, School of Pharmaceutical Sciences, Vels Institute of Science, Technology and Advanced Studies, Pallavaram, Chennai.
*Corresponding Author
Published In:
Volume - 12,
Issue - 2,
Year - 2022
ABSTRACT:
The study was aimed to evaluate the effect of Vitamin C adjuvant therapy significantly on lipid profile and HbA1c in diabetes patients with co-morbid cardiovascular disease.A total of 64 diabetic patients were enrolled by using a randomization procedure and assigned to control group and an intervention group.Patients in the intervention group received Vitamin C 500mg bid supplementation along with antidiabetic and antihyperlipdemic therapy as per the standard treatment protocol for a period of three months, whereas patients in the control group received only antidiabetic and antihyperlipidemic therapy for a period of three months. The mean age, BMI, duration of diabetes, of the subjects were 50.04±14.58, 27.94±4.71 and 9.93±4.83 respectively. The incidence of elevated CRP was found to be 68%. No statistically significant difference for any variable of comparison of glucose, lipid parameters and CRP was detected at baseline. There was a reduction in levels of clinical variables found after 3 months of daily use of vitamin C 500mg bid in the intervention group. Based on the results of this study concluded that Vitamin C as an adjuvant therapy produces beneficial effect in type 2 diabetes patients. Vitamin C 1g/day showed improved lipid profile which helps in cardiovascular risk mitigation.
Cite this article:
P. Geetha, M. Varaprasannarao, D. Subalakshmi, R. V. Bibi Bergin. Effect of Vitamin C Adjuvant Therapy on Lipid Profile in Diabetes patients with Co-Morbid Cardiovascular Disease. Asian Journal of Pharmacy and Technology. 2022; 12(2):125-8. doi: 10.52711/2231-5713.2022.00021
Cite(Electronic):
P. Geetha, M. Varaprasannarao, D. Subalakshmi, R. V. Bibi Bergin. Effect of Vitamin C Adjuvant Therapy on Lipid Profile in Diabetes patients with Co-Morbid Cardiovascular Disease. Asian Journal of Pharmacy and Technology. 2022; 12(2):125-8. doi: 10.52711/2231-5713.2022.00021 Available on: https://ajptonline.com/AbstractView.aspx?PID=2022-12-2-7
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