Author(s):
K. Srujana, B. Hemalatha, K. Padmalatha
Email(s):
balahemalatha25@gmail.com
DOI:
10.52711/2231-5713.2023.00012 
Address:
K. Srujana1, B. Hemalatha1*, K. Padmalatha2
1Department of Pharmaceutics, Vijaya Institute of Pharmaceutical Sciences for women, Vijayawada.
2Department of Pharmacology, Vijaya Institute of Pharmaceutical Sciences for women, Vijayawada.
*Corresponding Author
Published In:
Volume - 13,
Issue - 1,
Year - 2023
ABSTRACT:
Colon-specific drug delivery systems (CDDS) are advantageous for the treatment of a range of local diseases such as ulcerative colitis, Crohn’s disease, irritable bowel syndrome, chronic pancreatitis, and colonic cancer. Colon targeted drug delivery system can be utilized to deliver protein and peptide drugs as they that are known to degrade in the extreme gastric pH. These approaches involve the use of formulation components that interact with one or more aspects of gastrointestinal (GI) physiology, such as the variation in the pH along the GI tract, the occurrence of colonic microflora, and enzymes, to attain colon targeting. This article highlights the advantages, limitations and factors influencing colon-specific drug delivery. Further, the review gives information of various conventional, as well as relatively newer formulation approaches presently being utilized for the improvement of CDDS.
Cite this article:
K. Srujana, B. Hemalatha, K. Padmalatha. A Review on Colon Targeted Drug Delivery System. Asian Journal of Pharmacy and Technology. 2023; 13(1):57-4. doi: 10.52711/2231-5713.2023.00012
Cite(Electronic):
K. Srujana, B. Hemalatha, K. Padmalatha. A Review on Colon Targeted Drug Delivery System. Asian Journal of Pharmacy and Technology. 2023; 13(1):57-4. doi: 10.52711/2231-5713.2023.00012 Available on: https://ajptonline.com/AbstractView.aspx?PID=2023-13-1-12
REFERENCES:
1. Anil K. Philip, Betty Philip. Colon Targeted Drug Delivery Systems: A Review on Primary and Novel Approaches. Oman Medical Journal 2010; 25 (2): 70 – 78.
2. Obot Solomon Sunday. Colon specific drug delivery systems: Current trends and approaches. Universal Journal of Pharmaceutical Research 2017; 2 (4): 53 – 57.
3. Manoj Kumar Sarangi, M. E. Bhanoji Rao & Versha Parcha. Smart polymers for colon targeted drug delivery systems: a review. International Journal of Polymeric Materials and Polymeric Biomaterials 2020; 1130 - 1166.
4. Danda Sreelatha, Chandan Kumar Brahma. Colon targeted drug delivery – a review on primary and novel approaches. Journal of Global Trends in Pharmaceutical Sciences 2013; 4 (3): 1174 – 1183.
5. G. Sangeetha, M. Jubaitha Begum, S. Reddemma, Y. Rajendra. Colon targeted drug delivery system: a review. International Journal of Pharmacy & Technology 2011; 3 (4): 1657 - 1672.
6. Anita, Anil Singh and Ankit Dabral. A review on colon targeted drug delivery system. International Journal of Pharmaceutical Sciences and Research 2019; 10(1): 47 – 56.
7. Nishant Singh and Dr. R. C. Khanna. Colon targeted drug delivery systems – A Potential Approach. The Pharma Innovation 2012; 1 (1): 40 – 47.
8. Asha Patel, Nilam Bhatt, Dr. K. R. Patel, Dr. N. M. Patel, Dr. M. R. Patel. Colon targeted drug delivery system: A review system. Journal of Pharmaceutical Science and Bioscientific Research 2011; 1 (1): 37 - 49.
9. Sandeep Gapat, Mayuri Gaikwad, Vishwanath Morkhande, S. R. Sayyed, Yadav Vivek, Kure Sapana. A review on colon targeted drug delivery: An innovative approach. Indo American Journal of Pharmaceutical Research 2015; 5 (10): 3115 – 3127.
10. Jose S, Dhanya K, Cinu TA, Litty J, Chacko AJ. Colon Targeted Drug Delivery: Different Approaches. Young Pharm. 2009; 1: 13 - 19.
11. V. T. Iswariya, K. Sujitha, A. Ramyasree, B. Sravanthi. Review on Colon Targeted Drug Delivery System. IJPPR 2016; 7 (1): 642 – 658.
12. Manoj Kumar Sarangi, Sasmita Padhi. Colon targeted drug delivery system-an approach for treating colonic ailments. Journal of Critical Reviews 2015; 2 (4): 12 – 18.
13. Asija Rajesh, Chaudhari Bharat, Asija Sangeeta. Oral colon targeted drug delivery system: A review on current and novel perspectives. Journal of Pharmaceutical and Scientific Innovation 2012; 1(5): 6 – 12.
14. Lokesh Choudhary, Amit Jain, Dilip Agarwal. Colon Targeted Oral Drug Delivery Systems: A Review. Asian Journal of Pharmaceutical Research and Development 2020; 8(4): 186 - 190.
15. Nikita Sinha, Amit Kumar and Sonal Rai. A review on colon targeted drug delivery. International Journal of Current Research 2020; 12 (8): 13001 - 13004.
16. Bhandari Neeraj, Tangum, Bali Tanvi, Simran, Sumeena and Choudhary Swati. Colon targeted drug delivery system: A review. World Journal of Pharmacy and Pharmaceutical Sciences 2017; 6(4): 364 – 377.
17. Mobarak Hussain, Dr. Biswajit Das and Dr. Suvakanta Dash. Descriptive review on colon targeted drug delivery system. European Journal of Biomedical and Pharmaceutical Sciences 2017; 4(4): 522 – 530.
18. Sirisha. Recent Advacements on Colon Targeted Drug Delivery Systems. Asian Journal of Pharmaceutical Research 2020; 10 (4): 1 – 5.
19. Rutuja Sawant, Shreya Parkar, Prajackta Kegade, Akshay Gade. Colon Targeted Drug Delivery: A Review on Novel Approaches. Asian J. Res. Pharm. Sci. 2020; 10(4): 293 - 298.
20. Raditya Iswandana, Kurnia Sari Setio Putri, Fathia Amalia Putri, Maxius Gunawan, Sekar Arum Larasati. Challenge and Development Strategy for Colon-Targeted Drug Delivery System. Pharmaceutical Sciences and Research 2022; 9 (1): 17 - 27.
21. Altamash M. Qureshi, Munira Momin, Sudha Rathod, Asish Dev, Chaitrali Kute. Colon targeted drug delivery system: A review on current approaches. Indian Journal of Pharmaceutical and Biological Research 2013; 1 (4): 130 - 147.
22. Ratnaparkhi Mukesh P, Somvanshi Fattesingh U, Pawar Sham A, Chaudhari Shilpa P, Gupta Jyoti P, Budhavant Kalyani A. Colon targeted drug delivery system. International Journal of Pharma Research & Review 2013; 2 (8): 33 – 42.
23. Bhushan Prabhakar Kolte, Kalyani V. Tele, Vinayak S. Mundhe, Sandeep S. Lahoti. Colon Targeted Drug Delivery System – A Novel Perspective. Asian Journal of Biomedical and Pharmaceutical Sciences 2012; 2 (14): 21 - 28.
24. Rutuja P. Bugad, Dr. Sachinkumar V. Patil. A comprensive review on colon targeted drug delivery system. International Journal of Creative Research Thoughts 2021; 9 (7): 225 - 237.
25. Roberto Arevalo Pereza, Cristina Maderueloa, Jose M. Lanao. Recent advances in colon drug delivery systems. Journal of Controlled Release 2020; 327: 703 - 724.
26. Vaishali Chauhan, Harshita Mishra, Kapil Kumar. A comprehensive review on colon targeted drug delivery system. Global journal for research analysis 2019; 8 (1): 173 – 178.
27. Karishma Mahajan, Nishant Thakur, Kritika Thakur, Simran. Overview on Colon Targeting Drug Delivery System. Journal of Emerging Technologies and Innovative Research 2021; 8 (2): 2120 - 2137.
28. T M Litto, S D Shaiju, S Meenu. Colon Targeted Drug Delivery: A Review. J. Pharm. Sci. & Res. Vol. 2020; 12 (10): 1326 - 1331.
29. Singh Amritpal, Sharma Ankush, Pooja, Anju. Novel approaches for colon targeted drug delivery system. International Journal of Research and Development in Pharmacy and Life Sciences 2014; 3 (2): 877 – 886.
30. Sang Hoon Lee, Rajiv Bajracharya, Jeong Youn Min, Ji Won Han, Byeong Ju Park and Hyo-Kyung Han. Strategic Approaches for Colon Targeted Drug Delivery: An Overview of Recent Advancements. Pharmaceutics 2020; 12: 1 – 20.
31. H. Rajpurohit, P. Sharma, S. Sharma and A. Bhandari. Polymers for colon targeted drug delivery. Indian Journal of Pharmaceutical Sciences 2010; 72 (6): 689 – 696.
32. D Kajale, BV Bakade, MA Channawar, SR Gawande, RL Bakal, AV Chandewar. Colon Targeted Drug Delivery System – A Review. Research J. Pharm. and Tech. 2010; 3 (1): 45 – 49.