Author(s): Haridwar Lodh, Sheeba FR, Prabhat Kumar Chourasia, Harshitha Arun Pardhe, Pallavi N

Email(s): haridwar462@gmail.com

DOI: 10.5958/2231-5713.2020.00043.4   

Address: Haridwar Lodh1*, Sheeba FR1, Prabhat Kumar Chourasia1, Harshitha Arun Pardhe2, Pallavi N2
Mallige Collage of Pharmacy, Bangalore-560090, Karnataka, India.
*Corresponding Author

Published In:   Volume - 10,      Issue - 4,     Year - 2020


ABSTRACT:
Scientific and technological developments in the research and development of new drug delivery systems have been made in recent years by resolving physiological disorders, such as short gastric residence periods and unpredictable gastric emptying times. Dosage forms that can be hold within the stomach are called as Gastro-retentive Dosage Forms (GRDF). Multiple methods used in the prolongation of gastric residence time are floating drug delivery system, swelling and expanding system, polymeric bio-adhesive system, high density system and other delayed gastric emptying system. Medication-based disease treatment is entering a new era in which a increasing range of innovative drug delivery technologies are being used and are available for clinical use. Floating Drug Delivery Systems (FDDS) is one of the gastro-retentive dosage forms used to achieve extended duration of gastric residency. The aim of writing this review on floating drug delivery systems (FDDS) was to compile the recent literature with particular focus on the main floating mechanism to achieve gastric retention. Sustained oral release of gastrointestinal dosage types provides many benefits for drugs with absorption from the upper sections of the gastrointestinal tract and those that function locally throughout the stomach. This review includes the physiology, factors controlling gastric retention time, excipient variables influencing gastric retention, approaches to designing single-unit, hydro-dynamically balanced system and multi-unit floating structure, and aspects of their classification, formulation and evaluation are discussed in detail, and few applications of these systems.


Cite this article:
Haridwar Lodh, Sheeba FR, Prabhat Kumar Chourasia, Harshitha Arun Pardhe, Pallavi N. Floating Drug Delivery System: A Brief Review. Asian J. Pharm. Tech. 2020; 10(4):255-264. doi: 10.5958/2231-5713.2020.00043.4

Cite(Electronic):
Haridwar Lodh, Sheeba FR, Prabhat Kumar Chourasia, Harshitha Arun Pardhe, Pallavi N. Floating Drug Delivery System: A Brief Review. Asian J. Pharm. Tech. 2020; 10(4):255-264. doi: 10.5958/2231-5713.2020.00043.4   Available on: https://ajptonline.com/AbstractView.aspx?PID=2020-10-4-7


REFERENCE:
1.    Gupta P and Gnanarajan PK. Floating Drug Delivery System: A Review. International Journal of Pharma Research and Review. 2015; 4(8): 37-44.
2.    Shyama SK and Sivakumar R. Floating Drug Delivery System: An Updated Review. International Journal of Current Pharmaceutical and Clinical Research. 2014; 4(3):150-53.
3.    Parmar PD, Pande S, Shah HS, Sonara SN and Patel GH. Floating Drug Delivery System: A Novel Approach to Prolong Gastric Retention. World Journal of Pharmacy and Pharmaceutical Sciences. 2014; 3(4): 418-44.
4.    Veerareddy PR, Bajjuri S, Sanka K, Jukanti R, Bandari S and Ajmeru RK. Formulation and Evaluation of Gastroretentive Dosage Form of Ofloxacin. Stamford Journal of Pharmaceutical Sciences. 2011; 4(1): 09-18.–
5.    Nirmal J, Saisivam S, Peddanna C, Muralidharan S, Godwinkumar S and Nagarajan M. Bi-layer tablets of Atorvastatin Calcium and Nicotinic acid; Formulation and evaluation. Chemical and Pharmaceutical Bulletin. 2008; 56(10): 1455-58.
6.    Hamza Yassin El-Said and Mona HA. Design and In Vitro Evaluation of Novel Sustained-Release Double-Layer Tablets of Lornoxicam: Utility of Cyclodextrin and Xanthan Gum Combination. American Association of Pharmaceutical Scientists. 2009; 10(4):1357-67.
7.    Sarojini S and Manavalan R. An overview on various approaches to Gastroretentive dosage forms. International Journal of Drug Development and Research. 2012; 4(1): 01-13.
8.    Pawar VK, Kansal S, Garg G, Awasthi R, Singodia D and Kulkarni GT. Gastroretentive dosage forms: A review with special emphasis on floating drug delivery systems. Drug Delivery. 2010; 18(2): 97-110.
9.    Chawla G, Gupta P, Vishal K and Bansal AK. Gastroretention a Means to Address Regional Variability in Intestinal Drug Absorption. Pharmaceutical Technology. 2002; 27(7): 50-68.
10.    Mandal UK, Chatterjee B and Faria GS. Gastro-retentive drug delivery systems and their in vivo success: A recent update. Asian Journal of Pharmaceutical Sciences. 2016; 11(5): 575-84.
11.    Dixit N. Floating Drug Delivery System. Journal of Current Pharmaceutical Research. 2011; 7(1): 6-20.
12.    Jassal M, Nautiyal U, Kundlas J and Singh D. A review: Gastroretentive drug delivery system (grdds). Indian Journal of Pharmaceutical and Biological Research. 2015; 3(1):82-92.
13.    Gopalakrishnan S and Chenthilnathan A. Floating Drug Delivery Systems: A Review. Journal of Pharmaceutical Science and Technology. 2011; 3(2): 548-54.
14.    Rathod HJ, Mehta DP and Yadav JS. A review on Gastroretentive Drug Delivery Systems. Pharma Tutor. 2016; 4(7): 29-40.
15.    Rajeswari S and Prasanthi T. A recent review on dual release bilayered tablets. Critical Review in Pharmaceutical Sciences. 2016; 5(4): 1-10.
16.    Tripathi J, Thapa P, Maharjan R and Jeong SH. Current State and Future Perspectives on Gastroretentive Drug Delivery Systems. Pharmaceutics. 2019; 11(4): 1-22.
17.    Rastogi V, Kumar A, Yadav P and Hegde RR. Mathematical Optimization and Investigation on Polymeric Blend of Chitosan and Hydroxy Propyl Methyl Cellulose K4M for Sustained Release of Metronidazole. Asian Journal of Pharmaceutics.  2016; 9(6): S1-S11.
18.    Chien YM. Novel Drug Delivery System, 3rd Ed. Vol. 1. New York: Marcel Dekker 1992; 139-96.
19.    Vijayasundiram K, Puratchikody A, Prasanth VV and Ravichandiran V. Enhancement of Drugs Bioavailability by Floating Drug Delivery System – A Review. International Journal of Drug Delivery. 2011; 3(1): 558-70.
20.    Deshpande AA, Shah NH, Rhodes CT and Malick W. Development of a novel controlled-release system for gastric retention. Pharmaceutical Research. 1997; 14(1): 815-19.
21.    Patel DM, Patel MJ and Patel CN. Multi Particulate System: A Novel Approach in Gastro-Retentive Drug Delivery. International Journal of Ayurveda and Pharm Research. 2011; 2(4): 96-106.
22.    Kaushik AY, Tiwari AK and Gaur A. Role of Excipients and polymeric advancements in preparation of floating drug delivery systems. International Journal of Pharmaceutical Investigation. 2015; 5(1): 1-12.
23.    Bharkatiya M, Kitawat S and Ojha A. Floating drug delivery system: A review. Journal of Drug Delivery and Therapeutics. 2014; 4(2): 130-134.
24.    Tomar P, Shukla V, Kharia AA and Chatterjee DP. Floating drug delivery system: an updated review. Journal of Medical Pharmaceutical and Allied Science. 2013; 04: 31-42.
25.    Sharma N, Agarwal D, Gupta MK and Khinchi MP. A Comprehensive Review on Floating Drug Delivery System. International Journal of Research in Pharmaceutical and Biomedical Sciences. 2011; 2(2): 428-41.
26.    Gadhve MV, Lende LK, Tajane TS and Gaikwad DD. Formulation and Development of Bilayer Floating Tablet of Nifedipine using surface solid dispersion technique. International Journal of Advances in Pharmaceutics. 2016; 5(5): 117-26.
27.    Reddy RS, Ramachandra CT, Hiregoudar S, Nidoni UK, Kammar M, and Ram J. influence of processing conditions on functional and reconstitution properties of milk powder made from Osmanabadi goat milk by spray drying. Small Ruminant Research. 2014; 119: 130–137.
28.    Arunachalam A, Karthikeyan M, Kishore K, Prasad PH, Sethuraman S, Ashutosh kumar S and Manidipa S. Floating drug delivery systems: A review. International Journal of Research in Pharmaceutical Sciences. 2011; 2(1): 76-83.
29.    Arora S, Ali J, Ahuja A, Khar RK and Baboota S. Floating Drug Delivery Systems: A Review. American Association of Pharmaceutical Scientists. 2005; 6(3): 372-90.

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