Author(s): S. J. Beula, R. Suthakaran, M. Viswaja, CH. Shankar, G. Sree Lakshmi

Email(s): pharmjanet123@gmail.com

DOI: 10.52711/2231-5713.2023.00007   

Address: S. J. Beula1*, R. Suthakaran2, M. Viswaja3, CH. Shankar4, G. Sree Lakshmi5
1,4,5Teegala Ram Reddy College of Pharmacy, Meerpet, RR District, Telangana, India.
2,3Vijaya College of Pharmacy, Munuganoor, RR District, Telangana, India.
*Corresponding Author

Published In:   Volume - 13,      Issue - 1,     Year - 2023


ABSTRACT:
Traditional medicine from plant extracts has proved to be more affordable, clinically effective and relatively less adverse effects than modern drugs. The Present study was conducted for the extraction, Identification and Invitro anti diabetic activity of Gymnema sylvestre (Asclepiadaceae), extraction were employed to obtain maximum yield. The method where the leaves were extracted under continuous hot extraction in Soxhlet apparatus with 95% ethanol give the maximum yield. The extract were performed qualitative Studies of different chemical constituent of the plant. Gymnema Sylvestre ethanol extract have shown promising antidiabetic activity against standard control Alloxan.


Cite this article:
S. J. Beula, R. Suthakaran, M. Viswaja, CH. Shankar, G. Sree Lakshmi. Anti-diabetic effect of Gymnema sylvestre an Alloxan-Induced Diabetic in Male Albino Wistar Rats. Asian Journal of Pharmacy and Technology. 2023; 13(1):34-0. doi: 10.52711/2231-5713.2023.00007

Cite(Electronic):
S. J. Beula, R. Suthakaran, M. Viswaja, CH. Shankar, G. Sree Lakshmi. Anti-diabetic effect of Gymnema sylvestre an Alloxan-Induced Diabetic in Male Albino Wistar Rats. Asian Journal of Pharmacy and Technology. 2023; 13(1):34-0. doi: 10.52711/2231-5713.2023.00007   Available on: https://ajptonline.com/AbstractView.aspx?PID=2023-13-1-7


REFERENCES:
1.    Bhaskar Ananda Raj V, Janet Beula S, Suresh KumarS. Ethanobotanical and pharmacognostical study of Givotia moluccana bark. International Journal of Pharmaceutical research and Development, 2012, 4(07), pg 148- 154.
2.    Raina M.K. quality control of herbal and herbo- mineral formulations. Indian Journal of natural products, 2003, 19, pg 11-15
3.    Mukesh S Sikarwar, Patil M.B. Anti- hyperlipidemic activity of Salacia chinensis root extract in triton induced and atherogenic diet induced hyperlipidemic rats. Indian Journal of Pharmacology, 2012, 44(1), pg 88-92.
4.    Wealth of India. A Dictionary of Indian Raw materials and Industrial Products, National Institute of Science Communication, Council of Scientific and Industrial Research. New Delhi, Raw material. 10: 100-107. 2002.
5.    Ivan AR. Medicinal plant of World: Chemical Constituents, Traditional Uses and Modern Medicinal Uses, Human Press Totowa, New Jersey. 2006, pg 283-289.
6.    Jain SR, Sharma SN. Hypoglycemic drugs of Indian indigenous origin. Plant Medica. 1967 Nov, 15(04), pg 439-42.
7.    Singh N, Gupta M. Effects of ethanolic extract of Syzygium cumini (Linn) seed powder on pancreatic islets of alloxan diabetic rats. Indian Journal of Experimental Biology. 2007, 45, pg 861-867.
8.    Teixeira CC, Weinert LS, Barbosa DC, Ricken C, Esteves JF, Fuchs FD. Syzygium cumini (L.) Skeels in the treatment of type 2 diabetes. Diabetes Care. 2004 Dec 1, 27(12), pg 3019-20.
9.    Manohar SH, Naik PM, Praveen N, Murthy HN. Distribution of gymnemic acid in various organs of Gymnema sylvestre. Journal of Forestry Research. 2009, 20(3):pg68–270.
10.    Singh VK, Umar S, Ansari SA, Iqbal M. Gymnema sylvestre for diabetics. Journal of Herbs, Spices and Medicinal Plants. 2008, 14(1-2) pg 88–106.
11.    Kanetkar P, Singhal R, Kamat M. Gymnema sylvestre. A memoir. Journal of Clinical Biochemistry and Nutrition. 2007, 41(2), pg 77–81.
12.    Saneja A, Sharma C, Aneja KR, Pahwa R. Gymnema Sylvestre (Gurmar). A review. Der Pharmacia Lettre. 2010, 2(1), pg 275–284.
13.    Bhaskar Ananda Raj V, Murugamani V, Anusha CH, Indraja N. Preliminary pharmacognostical evaluation of Givotia Moluccana leaves. International Journal of Pharmacognosy and Phytochemical Research. 2012, 4(2), p g 74-78.
14.    Madhava Chetty K, Sivaji K, Tulasi Rao K. Flowering Plants of Chitoor District, A.P.India, 3rd ed; 2008(1),pg 185, 317.
15.    Mukherjee P.K. Quality Control of Herbal Drugs. Business Horizons, New Delhi 200,:pg 187-191.
16.    Raman N. Phytochemical Techniques.1sted; New India Publications, New Delhi, 2006, pg 19-25.
17.    Kokate CK, Purohit AP, Gokhale S.B .Methods of crude drug evaluation Pharmacognosy, Nirali Prakashan, Pune, 1995, pg 88-99.
18.    Rafiullah M.R.M, Siddiqui A.W, Ali M. Antidiabetic Activity of Some Indian Medicinal Plants. Pharmaceutical Biology.2006, 44(6), pg 95-99.
19.    Kifle Z.D,  Yesuf J.S,  Atnafie S.A. Evaluation of in vitro and in vivo anti-diabetic, anti-hyperlipidemic and anti-oxidant activity of flower crude extract and solvent fractions of hagenia abyssinica (rosaceae).Journal of  Experimental Pharmacology, 2020(12), pg. 151.
20.    Belayneh Y.M, Birru E.M, Ambikar D. Evaluation of hypoglycemic, antihyperglycemic and antihyperlipidemic activities of 80% methanolic seed extract of Calpurnia aurea Benth in mice. Journal of Experimental Pharmacology, 2019(11), pg 73.

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DOI: 10.5958/2231–5713 


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