ABSTRACT:
Cubosomes, sometimes called bicontinuous cubic phase liquid crystals, are nanoparticles with a structure mostly composed of specific amphiphilic lipids in a predetermined ratio. Cubosomes are typically formed by hydrating a polar lipid or surfactant that forms a cubic phase, followed by the dispersion of a solid-like phase into smaller particles. They exhibit solid-likerheology and have certain qualities that are useful. Their carvenous (honeycomb) structures are tightly packed and twisted into three-dimensional bilayers, and they possess thermodynamic stability. Their complicated structure enables them to have a higher capacity for drug loading. Cubosomes are able to enclose hydrophilic, amphiphilic, and hydrophobic substances. Poorly soluble drugs can become more soluble with the help of cubosomes. Cubosome dispersions are both biocompatible and bioadhesive. Due to their characteristics, cubosomes are adaptable systems that can be administered orally, subcutaneously, or parenterally. Cubosome structure using electron microscopy, light scattering, x-rays, and NMR; yet, not many researchers have looked at the cubosome's potential as a delivery mechanism.
Cite this article:
Ashish Kumar, Dinesh Kumar Kashyap, Anjali, Kapil Kumar Verma. A Review on Cubosome: The Novel Drug Delivery Systems. Asian Journal of Pharmacy and Technology. Tech. 2024; 14(1):50-4. doi: 10.52711/2231-5713.2024.00010
Cite(Electronic):
Ashish Kumar, Dinesh Kumar Kashyap, Anjali, Kapil Kumar Verma. A Review on Cubosome: The Novel Drug Delivery Systems. Asian Journal of Pharmacy and Technology. Tech. 2024; 14(1):50-4. doi: 10.52711/2231-5713.2024.00010 Available on: https://ajptonline.com/AbstractView.aspx?PID=2024-14-1-10
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