Author(s): Junaid S. Shaikh, Shashikant. D. Barhate

Email(s): skjunaid.pharm@gmail.com

DOI: 10.52711/2231-5713.2024.00003   

Address: Junaid S. Shaikh*, Shashikant. D. Barhate
Shree Sureshdada Jain College of Pharmacy, Jamner, Dist, Jalgaon.
*Corresponding Author

Published In:   Volume - 14,      Issue - 1,     Year - 2024


ABSTRACT:
Emulgel have emerged as an auspicious drug delivery system for the delivery of hydrophobic drugs. The impartial of the study was to prepare emulgel of ketoprofen, a non-steroidal anti-inflammatory drug, using Carbopol 940 as a gelling agent. Mentha oil and clove oil were used as diffusion enhancers. The emulsion was prepared and it was combined in a gel base. The formulations were evaluated for spreading coefficient studies, rheological studies, and ex vivo release studies. Formulations F2 and F3 show maximum release. So, it can be concluded that topical emulgel of ketoprofen possesses an effective anti-inflammatory and analgesic activity.


Cite this article:
Junaid S. Shaikh, Shashikant. D. Barhate. Formulation and Evaluation of Ketoprofen Emulgel for Topical Drug Delivery System. Asian Journal of Pharmacy and Technology. Tech. 2024; 14(1):9-2 doi: 10.52711/2231-5713.2024.00003

Cite(Electronic):
Junaid S. Shaikh, Shashikant. D. Barhate. Formulation and Evaluation of Ketoprofen Emulgel for Topical Drug Delivery System. Asian Journal of Pharmacy and Technology. Tech. 2024; 14(1):9-2 doi: 10.52711/2231-5713.2024.00003   Available on: https://ajptonline.com/AbstractView.aspx?PID=2024-14-1-3


REFERENCES:
1.    Lionberger DR, Brennan MJ. Topical nonsteroidal anti-inflammatory drugs for the treatment of pain due to soft tissue injury: diclofenac topical patch. J Pain Research. 2010; 3: 223–233
2.    Kumar L, Verma R. In vitro evaluation of topical gel prepared using natural polymer. International Journal of Drug Delivery. 2;2010: 58–63.2
3.    Gennaro, AR. (Ed.), 1995. Remington: the Science and Practice of Pharmacy, 19th ed. Mack Publishing Company, Easton.
4.    Mohamed, M.I., 2004. Optimization of chlorphenesin emulgel formulation. AAPS J. 6
5.    Gupta, A., Mishra, A. K., Singh, A. K., Gupta, V., Bansal, P., 2010. Formulation and evaluation of topical gel of diclofenac sodium using different polymers. Drug Invention Today. 2, 250–253.
6.    Stanos, S.P., 2007. Topical agents for the management of Musculoskeletal pain. J. Pain Sympt. Manage. 3
7.    Jain, A., Deveda, P., Vyas, N., Chauhan, J., et al., 2011. Development of antifungal emulsion-based gel for topical fungal infection. IJPRD 2 (03).
8.    Panwar S,Upadhyay N, Bairagi N ,et. al. Emulgel : A Review Asian Journal of Pharmacy And Life Sciences. 2011; 1(3): 333-342
9.    Abd El-Bary, S. Shalaby, and S. Abd El-A al. Formulation and stability of chloramphenicol gel and emulgel. Bulletin of Faculty of Pharmacy, Cairo University. 2001; 39: 89–99
10.    Barry B. Novel mechanisms and devices to enable successful transdermal drug delivery. European Journal of Pharmaceutical Sciences. 2001: 101-114
11.    Buck P. Skin barrier function: effect or age, race inflammatory Disease the International Journal of Aromatherapy. 2004; 1: 70 – 72.
12.    Purdon, C, Azzi G, Zhang J, Smith E. Penetration enhancement of transdermal delivery - current permutation and limitations. Critical Review in Therapeutic Drug Carrier. 2004; 21: 97 - 132.
13.    Gungor S, Bergisadi N. In vitro release studies on Topical gel formulation of Nimesulide. 2003: 155-156
14.    Schreier, H., Bouwstra, J.A. Liposomes and Niosomes as topical drug carriers: Dermal and Transdermal delivery. J. Contr. Rel. 1985; 30: 863–868.
15.    Khullar R, Kumar D, Seth N, et.al. Formulation And Evaluation Of Mefenamic Acid Emulgel For Topical Delivery.  Saudi Pharmaceutical Journal. 2012: 20; 63-67 .









Recomonded Articles:

Author(s): A. K. Meena, Jyoti Meena, Ankush Jadhav, M. M. Padhi

DOI:         Access: Open Access Read More

Author(s): Anuradha A Sawant, S.K. Mohite.

DOI: 10.5958/2231-5713.2015.00014.8         Access: Open Access Read More

Author(s): Chaudhari R. D, Girase P. R, Suryawanshi H. P, Pawar S. P

DOI: 10.5958/2231-5713.2018.00025.9         Access: Open Access Read More

Author(s): Rutuja Saurabh Shah

DOI: 10.52711/2231-5713.2021.00035         Access: Open Access Read More

Author(s): Sushil D. Patil, Mukul J. Gupta, Kaustubh S. Kote, Mr. Rajendran R

DOI: 10.5958/2231-5713.2019.00039.4         Access: Open Access Read More

Author(s): Swati Siddheshwar Londhe, Mangesh Gautam Bhosale, Amol Arun Joshi

DOI: 10.5958/2231-5713.2020.00041.0         Access: Open Access Read More

Author(s): Basavaraj, Someswara Rao B, S.V Kulkarni, Pramod Patil , Chetan Surpur

DOI:         Access: Open Access Read More

Author(s): Debarshi Kar Mahapatra , Ruchi S. Shivhare , Vinod G. Ugale

DOI: 10.5958/2231-5713.2018.00008.9         Access: Open Access Read More

Author(s): Mayuresh. R. Redkar, Priyajit S Hasabe, Suraj. T. Jadhav, Pankaj S Mane, Deepak J Kare

DOI: 10.5958/2231-5713.2019.00038.2         Access: Open Access Read More

Author(s): Prajapati Krishna V., Jain Vinit C., Prajapati Neelam

DOI: 10.5958/2231-5713.2016.00007.6         Access: Open Access Read More

Author(s): S. Rawat, Akhilesh Gupta

DOI:         Access: Open Access Read More

Author(s): Hemlata Bhawar, Nachiket Dighe, Pankaj Shinde, Ravi Lawre, Sanjay Bhawar

DOI:         Access: Open Access Read More

Author(s): Sujata S. Sawant, Sangram S. Patil, Hemant S. Kandle, Manohar D. Kengar, Ganesh B. Vambhurkar, Mangesh A. Bhutkar

DOI: 10.5958/2231-5713.2019.00029.1         Access: Open Access Read More

Author(s): Anita S. Godase, Nayana V. Pimpodkar, Yogita R. Indalkar

DOI: 10.5958/2231-5713.2015.00030.6         Access: Open Access Read More

Author(s): Brijesh Kumar Saroj, Shreyash Tripathi, Mohd Yaqub Khan

DOI: 10.5958/2231-5713.2018.00034.X         Access: Open Access Read More

Author(s): Bindu Sree Koduru, Akshay R. Shinde, P. Jaya Preeti, K. Pavan Kumar, R. Rajavel, T. Sivakumar

DOI:         Access: Open Access Read More

Asian Journal of Pharmacy and Technology (AJPTech.) is an international, peer-reviewed journal, devoted to pharmaceutical sciences...... Read more >>>

RNI: Not Available                     
DOI: 10.5958/2231–5713 


Recent Articles




Tags