Hydrogels are three-dimensional, hydrophilic, polymericnetworks capable of absorbing large amounts of water orbiological fluids. Due to their high water content, porosity and soft consistency, they closely simulate natural livingtissue, more so than any other class of synthetic biomaterials. Furthermore, hydrogels can be formulated in a variety of physical forms, including slabs, microparticles, nano-particles, coatings, and films. As a result, hydrogels are commonly used in clinical practice and medicine for a wide range of applications, including Tissue engineering and Regenerative medicine, Diagnostics, Cellular immobilization, separation of biomolecules or cells, and barrier materials to regulate biological adhesions. Hydrogels are also relatively deformable and can conform to the shape of the surface to which they are applied. In the latter context, the mucoadhesive or bioadhesive properties of some hydrogelscan be advantageous in immobilizing them at the site ofapplication or in applying them on surfaces that are not horizontal. They have started to create a niche in severalfields of medicine like in specific site drug delivery, tissue reconstruction and tissue engineering and even as biosensors.In this review article an attempt has been made to explain the properties of hydrogels, their methods of preparation and it’s applications.
Cite this article:
Jayesh S. Gharat, Yogita V. Dalvi. Compressive Review on Hydrogel. Asian J. Pharm. Tech. 2018; 8 (3):172-181 . doi: 10.5958/2231-5713.2018.00028.4