Comprehensive Review on Phytopharmacological Potential of Gymnema sylvestre

Amiza; Ghazala Yaseen; Sammia Shahid

doi:10.5958/2231-5713.2020.00036.7

Asian Journal of Pharmacy and Technology

ISSN

2231-5713 (Online)
2231-5705 (Print)

Submit Article

Comprehensive Review on Phytopharmacological Potential of Gymnema sylvestre

Author(s): Amiza, Ghazala Yaseen, Sammia Shahid

Email(s): F2019140008@umt.edu.pk

DOI: 10.5958/2231-5713.2020.00036.7

Address: Amiza*, Ghazala Yaseen, Dr. Sammia Shahid
Department of Chemistry, School of Science, University of Management and Technology, Lahore, Pakistan.
*Corresponding Author

Published In: Volume - 10, Issue - 3, Year - 2020

View HTML

View PDF

ABSTRACT:
Therapeutic plants are of great interest as revolutionizing therapeutic agents in recent years for the treatment of several diseases. Gymnema sylvestre is commonly cultivated in India, member of the Apocynaceae family and also distributed in the various regions of Asia, Australia and Africa. It is extensively used in the Ayurvedic and traditional drug system, also it is the most promising plant used to cure diabetes mellitus. It is used as sweet paralyzing agent due to the existence of important phytochemicals constituents like gurmarin, gymnemic acids and gymneasaponins. It explore a wide range of health-giving effects as an effectualnatural remedy for diabetes, bronchitis and leukodema. It has been reported that G.sylestre has anti-diabetes, anti-obesity, antiviral, antidote of snake venom, anti-microbial and hypolipidaemic activities. This review has explore different phytochemicals as well as pharmacological potential of G.sylvestre.

Keywords:

Cite this article:
Amiza, Ghazala Yaseen, Sammia Shahid. Comprehensive Review on Phytopharmacological Potential of Gymnema sylvestre. Asian J. Pharm. Tech. 2020; 10(3):217-220. doi: 10.5958/2231-5713.2020.00036.7

Cite(Electronic):
Amiza, Ghazala Yaseen, Sammia Shahid. Comprehensive Review on Phytopharmacological Potential of Gymnema sylvestre. Asian J. Pharm. Tech. 2020; 10(3):217-220. doi: 10.5958/2231-5713.2020.00036.7 Available on: https://ajptonline.com/AbstractView.aspx?PID=2020-10-3-15

REFERENCES:

1. Srivastav, V. K.; Egbuna, C.; Tiwari, M., Plant secondary metabolites as lead compounds for the production of potent drugs. In Phytochemicals as Lead Compounds for New Drug Discovery, Elsevier: 2020; pp 3-14.

2. Laha, S.; Paul, S., Gymnema sylvestre (Gurmar): A Potent Herb with Anti-Diabetic and Antioxidant Potential. Pharmacognosy Journal 2019,11 (2).

3. Pham, H. T. T.; Hoang, M. C.; Ha, T. K. Q.; Dang, L. H.; Tran, V. O.; Nguyen, T. B. T.; Lee, C. H.; Oh, W. K., Discrimination of different geographic varieties of Gymnema sylvestre, an anti-sweet plant used for the treatment of type 2 diabetes. Phytochemistry 2018,150, 12-22.

4. Murthy, K. S.; Jyothi, R., Screening of phytoactives and antioxidant potentiality in Gymnema sylvestre. Journal of Drug Delivery and Therapeutics 2019,9 (4), 354-356.

5. Tahir, M.; Rasheed, M. A.; Niaz, Q.; Ashraf, M.; Anjum, A. A.; Ahmed, M. U., Evaluation of Antibacterial Effect of Gymnema sylvestre R. Br. Species Cultivated in Pakistan. Pakistan Veterinary Journal 2017,37 (3).

6. Yadav, S.; Nand, P.; Gupta, R. K., Formulation and phytochemicals characterization of polyherbal (Tinospora cordifolia, Gymnema sylvestre, Pterocarpus marsupium and Acacia arabica) antidiabetic compressed tablet lozenges. Journal of Pharmacognosy and Phytochemistry 2015,4 (2).

7. Porchezhian, E.; Dobriyal, R., An overview on the advances of Gymnema sylvestre: chemistry, pharmacology and patents. Die Pharmazie-An International Journal of Pharmaceutical Sciences 2003,58 (1), 5-12.

8. Behera, S. K., Phytochemical Analysis and Antioxidant Activities of Gymnema sylvestre R. Br. Leaf Extracts. Free Radicals & Antioxidants 2019,9 (1).

9. Sarker, P.; Rahman, M. M.; Khan, F.; Ming, L. C.; Mohamed, I. N.; Zhao, C.; Rashid, M. A., Comprehensive Review on Phytochemicals, Pharmacological and Clinical Potentials of Gymnema sylvestre. Frontiers in pharmacology 2019,10, 1223.

10. Gunasekaran, V.; Srinivasan, S.; Rani, S. S., Potential antioxidant and antimicrobial activity of Gymnema sylvestre related to diabetes. Journal of Medicinal Plants 2019,7 (2), 05-11.

11. Triveni, K.; Lakshmi, V.; Shashidhara, S.; Anitha, S., Gymnema Sylvestre: a comprehensive review. Pharma Science Monitor 2012,3 (4).

12. Basa’ar, O.; Alrabie, A.; Fatema, S.; Farooqui, M., Screening of supercritical fluid extract of Gymnema sylvestre R. Br. roots for phytochemical and pharmacological analysis. International Journal of PharmTech Research 2017,10 (3), 131-138.

13. Saneja, A.; Sharma, C.; Aneja, K.; Pahwa, R., Gymnema sylvestre (Gurmar): A review. Der Pharmacia Lettre 2010, 2 (1), 275-284

14. Gurav, S.; Gulkari, V.; Duragkar, N.; Patil, A., Systemic review: Pharmacognosy, phytochemistry, pharmacology and clinical applications of Gymnema sylvestre R Br. Pharmacognosy reviews 2002,1 (2).

15. Tiwari, P.; Mishra, B.; Sangwan, N. In Phytochemical and pharmacological properties of Gymnema sylvestre: an important medicinal plant. BioMed. Research, International: 2014.

16. Ahirwal, L.; Singh, S.; Dubey, M. K.; Bharti, V.; Mehta, A.; Shukla, S., In vivo immunomodulatory effects of the methanolic leaf extract of Gymnema sylvestre in Swiss albino mice. Archives of Biological Sciences 2015,67 (2), 561-570.

17. Maideen, N. M. P.; Balasubramaniam, R., Pharmacologically relevant drug interactions of sulfonylurea antidiabetics with common herbs. Journal of Herbmed Pharmacology 2018,7 (3).

18. Aralelimath, V. R.; bhise, s. B., anti-diabetic effects of gymnema sylvester extract on streptozotocin induced diabetic rats and possible β-cell protective and regenerative evaluations. Digest journal of nanomaterials & biostructures (djnb) 2012,7 (1).

19. Kumar, P.; Rani, S.; Arunjyothi, B., Chakrapani, P.; Rojarani, A., Evaluation of antidiabetic activity of Gymnema sylvestre and Andrographis paniculata in streptozotocin Induced diabetic rats. Int. J. Pharmacogn. Phytochem. Res 2017,9, 22-25.

20. Verma, N.; Shakya, V.; Saxena, R., Antidiabetic activity of glycoside isolated from Gymnema sylvestre in streptozotocin induced diabetic rats. Asian Journal of Chemistry 2008,20 (7), 5033.

21. Sathya, S.; Kokilavani, R.; Gurusamy, K., Hypoglycemic effect of Gymnema sylvestre (retz.,) R. Br leaf in normal and alloxan induced diabetic rats. Ancient science of life 2008,28 (2), 12.

22. R.K. Satdive, P. Abhilash, P.F. Devanand. Fitoterapia, 2003, 74,699-701

23. A. Bishayee, M. Chatterjee. Phyt Res, 1994, 8(2), 118-20.

24. P.R. Rachh, M.R. Rachh, N.R. Ghadiya, D.C. Modi, K.P. Modi, N.M. Patel, M.T. Rupareliya. Int J Pharmacol, 2010, 1-4.

25. Sinsheimer, J. E.; Rao, G. S.; McIlhenny, H. M.; Smith, R. V.; Maassab, H. F.; Cochran, K. W.: Experientia .1986,24, 302.

26. Kini, R. M.; Gowda, T. V.: Indian J. Biochem. Biophys1982, 19, 342.

27. Kini, R. M.; Gowda, T. V.: Indian J. Biochem. Biophys.1982,19, 152.

Recomonded Articles:

Pharmaceutical Aids – a Review Study

Author(s): Hafsa, Asfa, Nuha Rasheed, Abdul Saleem Mohammad

DOI: 10.5958/2231-5713.2017.00001.0 Access: Open Access Read More

Pharmaceutical Importance of Anti-Microbials

Author(s): Safa Mohammed Sadiq, Amtul Kareem, Nuha Rasheed, Abdul Saleem Mohammad

DOI: 10.5958/2231-5713.2017.00002.2 Access: Open Access Read More

Volvariella volvacea: A Macrofungus Having Nutritional and Health Potential

Author(s): Amit Roy, Pushpa Prasad, Nirmala Gupta

DOI: Access: Open Access Read More

A review on Hiptage benghalensis (Madhavilata) used as an Ayurvedic drug

Author(s): A. K. Meena, Jyoti Meena, Ankush Jadhav, M. M. Padhi

DOI: Access: Open Access Read More

Praecitrullus fistulosus: A Miraculous Plant

Author(s): Shweta Gautam, Priya Singh, Yogesh Shivhare

DOI: Access: Open Access Read More

Development and Evaluation of Dashmula plants of Ayurveda.

Author(s): Yogita. Chowdhary

DOI: 10.5958/2231-5713.2018.00002.8 Access: Open Access Read More

Review on Lawsonia inermis Linn. : An Update

Author(s): Kruti M. Patel, Pratik R. Patel

DOI: 10.5958/2231-5713.2017.00036.8 Access: Open Access Read More

Babchi (Psoralea corylifolia): From a Variety of Traditional Medicinal Application to its Novel Roles in Various Diseases: A Review

Author(s): Habeeba S. Shaikh, Siddiqua S. Shaikh

DOI: 10.52711/2231-5713.2021.00039 Access: Open Access Read More

Design and Development of Novel Synergistic Formulation of Pravastatin and Aspirin for the Treatment of Atherosclerosis and its Evaluation

Author(s): Pramod S. Salve, Nikhil Bali, Navleen Saini

DOI: 10.5958/2231-5713.2016.00009.X Access: Open Access Read More

Development of Novel HPTLC Method for Estimation of Qurcetine in Ocimum sanctum

Author(s): S. Rawat, Akhilesh Gupta

DOI: Access: Open Access Read More

Asian Journal of Pharmacy and Technology (AJPTech.) is an international, peer-reviewed journal, devoted to pharmaceutical sciences...... Read more >>>

RNI: Not Available
DOI: 10.5958/2231–5713