Author(s): Arijita Singla, Varsha Singh, Komal Kumari, Sonam Pathak, Arjun Singh

Email(s): arjunphar@gmail.com

DOI: 10.52711/2231-5713.2023.00042   

Address: Arijita Singla1, Varsha Singh1, Komal Kumari1, Sonam Pathak1, Arjun Singh2*
1Department of Pharmacology, School of Pharmaceutical Sciences, Bhagwant University, Sikar Road, Ajmer, Rajasthan 305004, India.
2Department of Medicine, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA 19107, United States.
*Corresponding Author

Published In:   Volume - 13,      Issue - 3,     Year - 2023


ABSTRACT:
Cancer remains a global challenge for clinicians and researchers alike, with an increasing mortality rate. Despite enormous progress in anticancer drug discovery, there is a constant demand for novel therapeutic agents due to resistance to existing chemotherapeutic drugs and their adverse side effects. Natural anticancer drugs have been shown to be both effective and safe in the treatment of cancer. Over 70% of the earth's surface and 95% of its tropical biosphere are covered by the oceans. 50% of the Earth's biodiversity, or 34 out of the 36 phyla, is made up of marine organisms. The majority of oceanic organisms are members of the marine flora, which also includes sponges, seaweed, algae, cyanobacteria, and marine fungi. These marine sources have created a significant opportunity for the discovery of novel anticancer compounds due to their taxonomically diverse and biological characteristics. Numerous marine compounds with potent anticancer properties have recently been identified, and clinical studies have demonstrated their effectiveness. The majority of them are sulfated polysaccharides and polyphenols, which are renowned for their powerful antioxidant, antitumor. Thus, the current chapter focuses on natural anticancer compounds and their derivatives that are undergoing clinical trials.


Cite this article:
Arijita Singla, Varsha Singh, Komal Kumari, Sonam Pathak, Arjun Singh. Natural Marine Anticancer compounds and their derivatives used in Clinical Trials. Asian Journal of Pharmacy and Technology. 2023; 13(3):235-9. doi: 10.52711/2231-5713.2023.00042

Cite(Electronic):
Arijita Singla, Varsha Singh, Komal Kumari, Sonam Pathak, Arjun Singh. Natural Marine Anticancer compounds and their derivatives used in Clinical Trials. Asian Journal of Pharmacy and Technology. 2023; 13(3):235-9. doi: 10.52711/2231-5713.2023.00042   Available on: https://ajptonline.com/AbstractView.aspx?PID=2023-13-3-15


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