Author(s):
A.V.S. Himabindu, G. Krupamai, K. Pravallika, U. Saranya, P. Kavya, S. Devika, K. Padmalatha
Email(s):
satyahimabindu@gmail.com
DOI:
10.52711/2231-5713.2025.00016
Address:
A.V.S. Himabindu*, G. Krupamai, K. Pravallika, U. Saranya, P. Kavya, S. Devika, K. Padmalatha
Department of Pharmaceutics, Vijaya Institute of Pharmaceutical Sciences for Women, Enikepadu, Vijayawada -521108, Andhra Pradesh, India.
*Corresponding Author
Published In:
Volume - 15,
Issue - 1,
Year - 2025
ABSTRACT:
Nanorobotics is a new field of study that has the potential to improve targeted delivery to specific parts of the body. Nanorobots are extremely small devices (50-100 nm diameter) designed to deliver medications to specific cells or tissues, potentially increasing treatment efficacy while reducing toxic effects. Advantage of nanorobots is that they can be equipped with sensors that detect changes in their surroundings, allowing medications to be released precisely when and where they are required. This study also discusses their potential impact on targeted drug delivery, disease diagnosis and biomedical applications.
Cite this article:
A.V.S. Himabindu, G. Krupamai, K. Pravallika, U. Saranya, P. Kavya, S. Devika, K. Padmalatha. Nanorobotics in Targeted Drug Delivery System. Asian Journal of Pharmacy and Technology. 2025; 15(1):95-0. doi: 10.52711/2231-5713.2025.00016
Cite(Electronic):
A.V.S. Himabindu, G. Krupamai, K. Pravallika, U. Saranya, P. Kavya, S. Devika, K. Padmalatha. Nanorobotics in Targeted Drug Delivery System. Asian Journal of Pharmacy and Technology. 2025; 15(1):95-0. doi: 10.52711/2231-5713.2025.00016 Available on: https://ajptonline.com/AbstractView.aspx?PID=2025-15-1-16
REFERENCES:
1. Khusainov R, Sushko S, Zuev V, et al. Nanorobotics: From molecular machines to functional systems. Nanotechnology. 2021; 32(6): 065301.
2. Lu Y, Xie L, Yang L, et al. Molecular machines in nanorobotics: Progress and challenges. Nanomedicine: Nanotechnology, Biology, and Medicine. 2020; 24: 102148.
3. Bolechová T, Průša F, Růžička M. Design and development of molecular nanorobots for drug delivery systems. Nanomaterials. 2019; 9(9): 1184. doi:10.3390/nano9091184.
4. Jafari M, Wang Z, Fuchs H. The role of self-assembly in nanorobotics: A review. Journal of Nanoscience and Nanotechnology. 2018; 18(8): 5269-5282.
5. Ramezani M, Nguyen T, Sadeghi M. Autonomous nanorobotic systems: Current challenges and future perspectives. Frontiers in Robotics and AI. 2020; 7: 27.
6. Martinez JS, Bosse A, Cremer PS, et al. DNA nanorobots for targeted drug delivery. Nature Nanotechnology. 2020;15(2):112-119.
7. Reches M, Rousso I, Gvirtsman H, et al. DNA-based nanorobots for targeted therapy. Nature Communications. 2021; 12(1): 2063.
8. Schmidt C. The future of medicine: Nanorobots in surgery. Nature Medicine. 2019; 25(5): 724-728.
9. Benassi E, Bandiera A, Cacciola R, et al. Nanorobots: A promising approach to targeted therapy in cancer. European Journal of Nanomedicine. 2021; 16(1): 9-21.
10. Liu X, Li Y, Yin J, et al. Nanorobotic technology in healthcare: A review. Artificial Cells, Nanomedicine, and Biotechnology. 2020; 48(1): 283-294.
11. Ibarra-Laclette E, Hernández-Pérez S, Gómez-Merino S, et al. Nanorobotics in precision medicine: Opportunities and challenges. Nature Reviews Bioengineering. 2022; 8(1): 14-27.
12. Gato-Álvarez C, Pérez S, Fidalgo M, et al. Nanorobotic techniques in drug delivery and cancer therapy. Nanomedicine: Nanotechnology, Biology, and Medicine. 2021; 30: 102281.
13. Yang H, Zhang Y, Zhang Q, et al. Engineering DNA nanorobots for cancer diagnosis and treatment. Frontiers in Bioengineering and Biotechnology. 2021; 9: 631007.
14. Patiño T, Zehner S, Baldi A, et al. Recent advances in programmable DNA-based nanorobots. Biomaterials. 2020; 245: 119982. doi:10.1016/j.biomaterials.2020.119982.
15. Leung L, Song X, Qiu X, et al. Development of DNA nanorobots for targeted drug delivery and imaging. Journal of Controlled Release. 2020; 320: 236-244.